Molecular Pathogenesis and Signal Transduction by Helicobacter pylori

Dr. rer. nat. Nicole TegtmeyerProf. Dr. rer. nat. Steffen BackertChair of MicrobiologyFriedrich Alexander University Erlangen/NurembergDepartment of Biology, Division of MicrobiologyStaudtstr. 591058 ErlangenGermany

• The human stomach in health and disease: infection strategies by Helicobacter pylori.- Human and Helicobacter pylori Interactions Determine the Outcome of Gastric Diseases.- Immune evasion strategies and persistence of Helicobacter pylori.- Recent advances in Helicobacter pylori replication: possible implications in adaptation to a pathogenic lifestyle and perspectives for drug design.- The Helicobacter pylori Methylome: Roles in Gene Regulation and Virulence.- Structural insights into Helicobacter pylori Cag protein interactions with host cell factors.- Gastric organoids: An emerging model system to study Helicobacter pylori pathogenesis.- DNA Transfer and Toll-Like Receptor Modulation by Helicobacter pylori.- Exploiting the gastric epithelial barrier: Helicobacter pylori’s attack on tight and adherens junctions.- Helicobacter pylori-induced Changes in Gastric Acid Secretion and Upper Gastrointestinal Disease.- Impact of the microbiota and gastric disease development by Helicobacter pylori.- Pathogenesis of gastric cancer: genetics and molecular classification.- Helicobacter pylori-mediated genetic instability and gastric carcinogenesis.- Helicobacter pylori and extragastric diseases.