Del 0 - Current Topics in Microbiology and Immunology

Type IV Secretion in Gram-Negative and Gram-Positive Bacteria

Inbunden, Engelska, 2018

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Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells.

Produktinformation

Utgivningsdatum2018-03-23
Mått155 x 235 x 28 mm
Vikt716 g
FormatInbunden
SpråkEngelska
SerieCurrent Topics in Microbiology and Immunology
Antal sidor345
Upplaga18001
FörlagSpringer International Publishing AG
ISBN9783319752402

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Prof. Dr. rer. nat. Steffen BackertChair of MicrobiologyFriedrich Alexander University Erlangen/NurembergDepartment of BiologyDivision of MicrobiologyStaudtstr. 5D-91058 ErlangenGermanyTel. ++49 9131 8528081Fax ++49 9131 8528082 Prof. Dr. techn. Elisabeth GrohmannProfessor of MicrobiologyBeuth University of Applied Sciences BerlinDepartment of Life Sciences and TechnologyDivision of MicrobiologyForum SeestraßeSeestr. 64D-13347 BerlinGermanyTel. ++49 30 45043942Fax ++49 30 45043983

Biological diversity of prokaryotic type IV secretion systems.- Evolution of type IV secretion systems and their substrates.- Structural and molecular biology of type IV secretion systems.- Relaxosome formation and transfer of broad-host range plasmids Gram-negative bacteria.- Mechanisms of conjugative transfer by Gram-positive broad-host range plasmids.- Social behavior and decision making in bacterial conjugation.- Structure and chemical biology approaches to understand type IV secretion system function and inhibition.- Type IV secretion systems: A pivotal tool to establish intracellular lifestyle by pathogens.- Subversion of host target cells by the Legionella type IV secretion system.- Role of multiple type IV secretion systems in Bartonella infections.- Requirements for T4SS effector protein translocation and function by the Coxiella Dot/Icm system.- Composition and function of the Helicobacter pylori cag type IV secretion system.- Secretion of chromosomal DNA by the gonococcal type IV secretion system.