Principles and Practices of Method Validation

• The Potential Use of Quality Control Data to Validate Pesticide Residue Method Performance;Optimization and Evaluation of Multi-Residue Methods for Priority Pesticides in Drinking and Related Waters;Validation of Analytical Data in a Research and Development Environment;Performance Validation of a Multi-Residue Method for 170 Pesticides in Kiwifruit;Effects of Sample Processing on Pesticide Residues in Fruit and Vegetables;Testing the Efficiency and Uncertainty of Sample Processing Using 14C-Labelled Chlorpyrifos: Part I Description of the Methodology;Testing the Efficiency and Uncertainty of Sample Processing Using 14C-Labelled Chlorpyrifos: Part II;Testing the Effect of Sample Processing and Storage on the Stability of Residues;AOAC International Collaborative Study on the Determination of Pesticide Residues in Nonfatty Foods by Supercritical Fluid Extraction and Gas Chromatography/Mass Spectrometry;Validation of Analytical Methods - Proving your Method is "Fit for Purpose";Validation of a Multi-Residue Method for Analysis of Pesticides in Fruit, Vegetables and Cereals by a GC/MS Iontrap System;Development and Validation of a Generic Gas Chromatographic Method for the Determination of Organophosphorus Pesticide Residues in Various Sample Extracts;Validation of Gas Chromatographic Databases for Qualitative Identification of Active Ingredients of Pesticide Residues;Estimation of Significance of "Matrix-Induced" Chromatographic Effects;Worked Example for Validation of a Multi-Residue Method;EU Guidance Documents on Residue Analytical Methods;Guidelines for Single-Laboratory Validation of Analytical Methods for Trace-Level Concentrations of Organic Chemicals;A Critique on Available In-House Method Validation Documentation;Subject Index.

"... any practising analyst dealing with method validation will find the examples presented in this book a useful source of technical information."