Explore the cutting edge of pharmaceutical innovation in this proceedings volume which brings together full-length research articles that spotlight the latest advancements across the dynamic landscape of drug discovery and development. From computational tools and green chemistry to breakthroughs in natural products, novel drug delivery systems, pharmacology, toxicology and biotechnology, this collection captures the interdisciplinary spirit of the CTD4-2025 conference. Contributions span a wide array of specialisations within pharmaceutical and life sciences, reflecting the vibrant exchange of ideas that took place among students, young researchers and leading experts from academia and industry.This book addresses the most pressing challenges in drug design, molecular targeting, resistance mechanisms and personalised medicine. Whether you are a seasoned researcher or an emerging scholar, you will find this volume a valuable resource for understanding the evolving paradigms that shape the future of therapeutic science.
Amalgamation of Bioinformatics and Computational Strategies to Unveil the Potential of Triphala Constituents Against Colorectal Cancer TargetsAmalgamation of Real-world Data and In Silico Techniques for Drug Repurposing Against Hepatocellular CarcinomaNovel Amino-pyrimidine Analogues as Potential Antibacterials Against E. coli: An Integrated In Silico and In Vitro StudyNovel Multimodal Parkinson’s Disease Diagnosis with BFO-JS Enhanced Random ForestExploring Novel PI3K-α Inhibitors for Pancreatic Cancer Through Computational ApproachML-driven Protein Function Prediction for Therapeutic DiscoverySynthesis, Characterization and Anti-tubercular Evaluation of Novel 4-amino-6-aryl-5-cyano-2-hydroxy Pyrimidine DerivativesPreliminary Phytochemical Screening, Physicochemical Evaluation, Standardization of Clitoria Ternatea ExtractsGreen and White Analytical Chemistry Perspectives in HPLC-based Estimation of Anti-hypertensive CombinationsDevelopment and Validation of Novel LC-MS/MS Method for the Simultaneous Quantification of Atoltivimab, Maftivimab, and Odesivimab in Human PlasmaAnalytical Method Development and Validation for the Simultaneous Estimation of Chlopidogrel and Aspirin in Bulk Drug and Pharmaceutical Dosage Form by Rp-HPLCPhytochemical Screening, UV Visible Spectrum and Thin Layer Chromatographic Studies on Leaves of the Averrhoa Bilimbi PlantA Validated Stability-indicating and Impurity Profiling UPLC Method for the Determination of AsciminibComparative Analysis of Trace Elements in Skin Whitening and Moisturing Creams Marketed in Indian Local Markets by ICP-OESInvestigating Comparative Controlled Drug Release Behavior of Various Types of Inorganic Ordered Mesoporous Silica Nanomaterials as a Carrier for Anticancer Drug Vinorelbine TartrateControlled Release of Anastrozole via Biodegradable Microspheres: A Novel Approach for Breast Cancer TreatmentDevelopment of Bepotastine Besilate Loaded Ocular in Situ Gels for Prolonged Release: An In-vitro and Ex-vivo Characterization StudyComparative Study of Disintegrants in the Formulation of Zopiclone Immediate Release TabletsDesign, Development, and Evaluation of a Tailored Topical Gel Containing Serratiopeptidase LiposomesPreparation and Quality Evaluation of Ciprofloxacin-based EmulgelPreparation and In-vitro Evaluation of Gel-based Polyherbal Hand SanitizerFormulation and Evaluation of Sustained Release Enalapril Maleate Microsponge TabletsInherent Immunological Activity of IgY Towards Peanut AllergensEpitope-based Vaccine Design for La Crosse Virus (LACV): A Computational Study Targeting Membrane GlycoproteinsEpitope-based Peptide Vaccine Design and Target Site Depiction Against Merkel Cell Carcinoma: An Immuno-informatics StudyAn Immunoinformatic Approach to Design and Optimization of Vaccine Against CEV Membrane Glyco PolyproteinSolvent-dependent Neuroprotective Efficacy of Excoecaria Crenulata Leaf ExtractsOptimization of Microwave-assisted Extraction Conditions for Total Flavonoids from Melia Azedarach L. and Its Effect on Cancer Cell SurvivalIdentifying the Underlying Molecular Mechanism of Alopecia Areata: A Network-based Approach Using Gene Expression DataCircumvention of Hepatotoxicity of Paracetamol by Co-administering with Chrysin in the Treatment of OsteoarthritisCytochrome P-450 Mediated Interactions in Narrow Therapeutic Index Drugs: A Preliminary Analysis Using Hospital Prescriptions and Computational ModellingPharmacological and Phytochemical Evaluation of Capparis Zeylanica Leaves for Antihyperlipidemic Activity Using in-vivo Models on RatsEvaluation of Anti-hypothyroid Activity of Hydroalcoholic Extract of Eichhornia Crassipes in Albino Wistar RatsCorrelation of Triglyceride Glycemic Index with Stroke Subtypes and OutcomesDehydrozingerone Mediated Neuroprotection in Alzheimer’s DiseaseNetwork Pharmacology and Simulation-based Evaluation of Doxylamine in Alzheimer’s DiseaseLisdexamphetamine as a Potential Hdac2 Inhibitor in Alzheimer's Disease: An Integrative Computational ApproachIn Silico Investigation of Pantoprazole as a Repurposed Histone Deacetylase 2 Inhibitor for Alzheimer's Therapy: Molecular Docking and Dynamics InsightsPrediction of Indole-3-carbinol Antidiabetic Effects Through Network Pharmacology ApproachNetwork Pharmacology-based Prediction of Indole-3-carbinol as a Multi-target Neuroprotective Agent Against Parkinson’s DiseaseAndrogen Receptor as a Target for Deltamethrin Metabolites: Implication for Endocrine DisruptionEvaluation of Anti-ulcerogenic Potential of Bismuth and Barium Oxide NanoparticlesCardio Care: Bridging the Knowledge Gap in Local CommunitiesKnowledge and Awareness of HPV Vaccination and Cervical Cancer Among Young AdultsCorticosteroids Usage in Specific Medical Conditions in a Tertiary Care Teaching HospitalA Study on Prescribing Pattern of Drugs Used in Psoriasis at a Tertiary Care HospitalRisk Correlation and Clinical Outcomes of Cardio-renal Syndrome in Post-covid-19 Patients: A Retrospective Observational StudyPatterns and Perceptions of Over-the-counter Drug Use Among Primary Care Patients in Hyderabad: A Mixed-methods StudyA Study on Polypharmacy, Potential Drug–Drug Interactions, and Appropriateness of Prescription Using Beers Criteria Among Elderly Patients in the Cardiology DepartmentSociodemographic and Lifestyle Factors Associated with Infertility in PCOSMedication Adherence Factors and Their Effects on Patient Quality of Life in a Tertiary Care Setting in Hypertensive and Diabetic PatientsBio Markers and Their Impact on Stroke Severity and Prognostic Value in Stroke PatientsComparison of Post-operative Pain and Analgesic Requirement Among Diabetic and Nondiabetic Patients: A Prospective Observational StudyThe Various Degrees of Malnutrition and Their Correlation with Feeding Methods Among Children Aged 6 Months to 2 YearsComparative Analysis of Cost-effectiveness and Drug Utilization of Amlodipine Versus Cilnidipine in Hypertension Management at a Tertiary Care Hospital