Advances in Immunology in China - Part B

Chen Dong is at Tsinghua University, Beijing, China Zhengfan Jiang is a Peking-Tsinghua Center for Life Sciences (CLS) Investigator, a tenured full professor and Vice Dean of the School of Life Sciences (SLS) at Peking University (PKU). He works on innate immunity and related cell signaling and, more specifically, on the molecular mechanisms of host defense against virus infection. His lab has identified ERIS which is also named STING and MITA and provided molecular insights into the coordination among viral infection-induced cytokine production, inflammation and apoptosis. Recently, his lab has identified Mn2+ as a critical component required for antiviral innate immunity by activating the cGAS-STING pathway. He has been honored to the National Science Foundation for Distinguished Young Scholars, China and the Cheung Kong Scholar and tenured full professor at PKU.

• 1. Deciphering the pathways to antiviral innate immunity and inflammationQing Yang and Hong-Bing Shu2. Tissue-resident NK cells and other innate lymphoid cellsJing Zhou, Zhigang Tian and Hui Peng3. The strategies of targeting the NLRP3 inflammasome to treat inflammatory diseasesHua Jiang, Tao Gong and Rongbin Zhou4. Fine-tuning of antiviral innate immunity by ubiquitinationYi Zheng and Chengjiang Gao5. Metabolic regulation of innate immunityShaonan Liang, Liangliang Ji, Lan Kang and Xiaoyu Hu6. Regulation of MHC class I-independent NK cell education by SLAM family receptorsShasha Chen, Dan Li, Yuande Wang, Qiaozhen Li and Zhongjun Dong7. Metalloimmunology: The metal ion-controlled immunityChenguang Wang, Rui Zhang, Xiaoming Wei, Mengze Lv and Zhengfan Jiang