Advances in Immunology in China - Part A

Chen Dong is at Tsinghua University, Beijing, China Zhengfan Jiang is a Peking-Tsinghua Center for Life Sciences (CLS) Investigator, a tenured full professor and Vice Dean of the School of Life Sciences (SLS) at Peking University (PKU). He works on innate immunity and related cell signaling and, more specifically, on the molecular mechanisms of host defense against virus infection. His lab has identified ERIS which is also named STING and MITA and provided molecular insights into the coordination among viral infection-induced cytokine production, inflammation and apoptosis. Recently, his lab has identified Mn2+ as a critical component required for antiviral innate immunity by activating the cGAS-STING pathway. He has been honored to the National Science Foundation for Distinguished Young Scholars, China and the Cheung Kong Scholar and tenured full professor at PKU.

• 1. Thymocyte selection: From signaling to epigenetic regulationJun Lyu, Lie Wang and Linrong Lu2. B cell mechanosensing: A mechanistic overviewSamina Shaheen, Zhengpeng Wan, Kabeer Haneef, Yingyue Zeng, Wang Jing and Wanli Liu3. Ionic protein–lipid interactions at the plasma membrane regulate the structure and function of immunoreceptorsHua Li, Chengsong Yan, Jun Guo and Chenqi Xu4. Non-canonical Hippo signaling regulates immune responsesLanfen Chen5. Molecular mechanisms of T helper 17 cell differentiation—Emerging roles for transcription cofactorsYu Jiang, Xiaohu Wang and Chen Dong6. T cell immune response within B-cell folliclesQizhao Huang, Lifan Xu and Lilin Ye7. Autoimmune diseases in ChinaRu Li, Xing Sun, Xu Liu, Yue Yang and Zhanguo Li8. Understanding tumor-infiltrating lymphocytes by single cell RNA sequencingXianwen Ren and Zemin Zhang