This book constitutes the proceedings of the 10th International Conference on Wireless Algorithms, Systems, and Applications, WASA 2015, held in Qufu, Shandong, China, in August 2015.The 36 revised full papers presented together with 5 revised short papers and 42 invited papers were carefully reviewed and selected from 133 initial submissions. The papers present current trends, challenges, and state-of-the-art solutions related to various issues in wireless networks. Topics of interests include effective and efficient state-of-the-art algorithm design and analysis, reliable and secure system development and implementations, experimental study and testbed validation, and new application exploration in wireless networks..