Medical-surgical nursing deals with complex system-based illnesses and the perioperative care that supports surgical recovery. This volume focuses on nuanced clinical reasoning for multisystem problems and high-acuity surgical care. Chapters integrate pathophysiology with advanced nursing assessments, invasive monitoring, and evidence-based interventions for organ-specific conditions. Detailed perioperative sections cover preoperative optimization, intraoperative considerations, and postoperative complications management. Learning tools—case scenarios, care bundles, and algorithms—promote decision-making at the bedside. Designed for senior students and practicing nurses, it bridges theory with the critical skills needed in surgical wards and high-dependency units.