Sustainable Synthesis of Pharmaceuticals

Using Transition Metal Complexes as Catalysts

Inbunden, Engelska, 2018

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There is a growing interest in the development of sustainable processes for the synthesis of pharmaceuticals and this book bridges the divide between industrial examples and the fundamental chemistry. It explains the basic principles of using transition metal catalysis with several green approaches for the synthesis of pharmaceuticals. The topic is an important one for green chemistry and the chapters in this book on hydroformylation, green oxidation and olefin metathesis will also be of interest to both medicinal and organic chemists.Written by leading experts in the field, it provides a valuable and easy tool for scientists and industrialists who require information regarding this topic.

Produktinformation

Utgivningsdatum2018-03-28
Mått156 x 234 x 21 mm
Vikt600 g
FormatInbunden
SpråkEngelska
SerieGreen Chemistry Series
Antal sidor286
FörlagRoyal Society of Chemistry
ISBN9781782629344

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James H Clark is Professor of Chemistry and Director of the Green Chemistry Centre of Excellence, The University of York, UK. He has led the green chemistry movement in Europe for the last 15 years and was the first scientific editor of the journal Green Chemistry and is Editor-in-chief of the RSC Green Chemistry book series. James H Clark is Professor of Chemistry and Director of the Green Chemistry Centre of Excellence, The University of York, UK. He has led the green chemistry movement in Europe for the last 15 years and was the first scientific editor of the journal Green Chemistry and is Editor-in-chief of the RSC Green Chemistry book series. University of Coimbra, Portugal Instituto de Tecnologia Química e Biológica, Portugal University of Lisbon, Portugal Universidade Federal de Minas Gerais, Brazil Louisiana State University, U.S.A.

Introduction;Transition Metals in Greener Pharmaceutical Chemistry;Sustainable Synthesis of Pharmaceuticals Using Alternative Techniques: Microwave, Sonochemistry and Mechanochemistry;Carbonylation Reactions in the Synthesis of Pharmaceutically Active Compounds;Applications of Catalytic Hydroformylation in the Synthesis of Biologically Relevant Synthons and Drugs;Transfer Hydrogenation with Non-toxic Metals for Drug Synthesis;Green Metal-catalysed Synthesis of Pharmaceutically Useful Asymmetric Epoxides and Sulfoxides;C–C Bond Formation in the Sustainable Synthesis of Pharmaceuticals;Metal-catalysed Metathesis Reactions for Greener Synthon/Drug Synthesis;Tetravalent Boron-based Therapeutics