Statistical Genetics of Quantitative Traits

Linkage, Maps and QTL

Inbunden, Engelska, 2007

Av Rongling Wu, Changxing Ma, George Casella

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This book intends to provide geneticists with the tools needed to understand and model the genetic variation for quantitative traits based on genomic data collected in mapping research and equip statisticians with the uniquenesses and ideas in relation to the exploration of genetic secrets using their computational skills. The emphasis of this book will be on non-human genetics.

Produktinformation

Utgivningsdatum2007-07-31
Mått155 x 235 x 27 mm
Vikt740 g
FormatInbunden
SpråkEngelska
SerieStatistics for Biology and Health
Antal sidor368
Upplaga2007
FörlagSpringer-Verlag New York Inc.
ISBN9780387203348

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Basic Genetics.- Basic Statistics.- Linkage Analysis and Map Construction.- A General Model for Linkage Analysis in Controlled Crosses.- Linkage Analysis with Recombinant Inbred Lines.- Linkage Analysis for Distorted and Misclassified Markers.- Special Considerations in Linkage Analysis.- Marker Analysis of Phenotypes.- The Structure of QTL Mapping.- Interval Mapping with Regression Analysis.- Interval Mapping by Maximum Likelihood Approach.- Threshold and Precision Analysis.- Composite QTL Mapping.- QTL Mapping in Outbred Pedigrees.

From the Reviews: "[I]t is a big help and guidance in the field of statistical developments for genetic mapping, synthesised all in one volume helping to build a bridge between genetics and statistics." (Lutz Bunger, Genetic Research, 89, 2007) "...[T]his is an ideal book for a young researcher looking for an exciting and developing field to get into." (International Statistics Review, April 2008)