"It is an informative review of the notable achievements of four great figures in medicine whose researches have virtually been eclipsed by the rapid advances of the 20th century." Paul Berg Stanford University Medical Center, USA "This timely book reminds us of the achievements and careers of the equally great scientific pioneers of a hundred years ago, who discovered most of the agents that cause major human diseases, and also revealed our main defence against infectious agents, the antibodies ... The author provides fascinating insights into the deliberations which resulted in well deserved awards for several scientific pioneers. This is an insiders' view of the strategy for choosing the right candidates for Nobel prizes." Tomas Lindahl Cancer Research UK London Research Institute