Adjunct Faculty, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland Ohio Formerly Professor, School of Nursing and Health Studies, University of Miami, Coral Gables Florida

• PART I: FOUNDATIONAL PHYSIOLOGIC CONCEPTSI.The Cell1.Cellular Biology, Regulation, and Control Mechanisms2.Cellular and Tissue Physiology3.Bioenergetics and Body Metabolism4.Body Fluid HomeostasisII.Genetics and Genomics5.Basic Genetics6.Patterns of Inheritance, Mitochondrial Inheritance, Epigeneticand Selected Associated DisordersIII.Inflammation, Immunity, Infection, and Cancer Biology7.Innate Immunity and Inflammation8.Adaptive Immunity9.Infectious Processes and Body Responses10.Abnormal Cell Growth and Cancer BiologyPART II: PATHOPHYSIOLOGY OF DISORDERS WITHIN SPECIFIC BODY SYSTEMSOXYGENATION AND PERFUSIONIV.Cardiovascular System11.Review of Cardiovascular Development, Structure, and Function 12.Vascular Disorders13.Cardiac Disorders14.Congenital Heart Disease Across the Lifespan15.Shock and Multiple Organ Dysfunction Syndrome V.Pulmonary System16.Review of Pulmonary Structure, Development, and Function 17.Congenital, Obstructive, and Restrictive Pulmonary Disorders18.Infectious Pulmonary Disorders and Lung CancerVI.Renal-Urinary System19.Review of Renal System Structure, Development, and Function20.Urinary Tract Disorders21.Kidney DisordersVII.Hematologic and Lymphatic System22.Chapter 22.Review of Hematologic System Development, Structure, and Function 23.Chapter 23.Hematologic and Lymphatic System Disorders SENSATION, MOBILITY, AND REGULATIONVIII.Nervous System24.Review of Nervous System Development, Structure, and Function 25.Central Nervous System Disorders26.Peripheral Nervous System Disorder27.Disorders of the Special Senses28.Mental Health DisordersIX.Musculoskeletal System29.Review of Musculoskeletal Development, Structure, and Function30.Muscle and Tendon Disorders31.Bone and Joint DisordersX.Endocrine System32.Review of Endocrine Structure, Function, and Interactions33.Disorders of the Hypothalamus, Pituitary Glands, and Adrenal Glands34.Disorders of the Thyroid Gland and the Parathyroid Glands35.Glycemic Control and Diabetes MellitusPROTECTION, NUTRITION, AND REPRODUCTIONXI.Disorders of Immunity36.Disorders of Reduced Immune Function37.Hypersensitivity and Autoimmune DisordersXII.Integumentary System38.Review of Integumentary Development, Structure, and Function39.Integumentary System DisorderXIII.Digestive System40.Review of Gastrointestinal Development, Structure, and Function 41.Disorders of the Mouth, Throat, Esophagus, and Stomach42.Disorders of the Small Intestine, Large Intestine, Pancreas, and Hepatobiliary System XIV.Reproductive Systems43.Review of Reproductive System Development, Structure, Function, and Sex Chromosome Abnormalities44.Common Disorders of the Female Reproductive System45.Male Reproductive Disorders46.Sexually Transmitted Infections47. Physiology and Pathophysiology of the Breast

Adjunct Faculty, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland Ohio Formerly Professor, School of Nursing and Health Studies, University of Miami, Coral Gables Florida

• PART I: FOUNDATIONAL PHYSIOLOGIC CONCEPTSI.The Cell1.Cellular Biology, Regulation, and Control Mechanisms2.Cellular and Tissue Physiology3.Bioenergetics and Body Metabolism4.Body Fluid HomeostasisII.Genetics and Genomics5.Basic Genetics6.Patterns of Inheritance, Mitochondrial Inheritance, Epigeneticand Selected Associated DisordersIII.Inflammation, Immunity, Infection, and Cancer Biology7.Innate Immunity and Inflammation8.Adaptive Immunity9.Infectious Processes and Body Responses10.Abnormal Cell Growth and Cancer BiologyPART II: PATHOPHYSIOLOGY OF DISORDERS WITHIN SPECIFIC BODY SYSTEMSOXYGENATION AND PERFUSIONIV.Cardiovascular System11.Review of Cardiovascular Development, Structure, and Function 12.Vascular Disorders13.Cardiac Disorders14.Congenital Heart Disease Across the Lifespan15.Shock and Multiple Organ Dysfunction Syndrome V.Pulmonary System16.Review of Pulmonary Structure, Development, and Function 17.Congenital, Obstructive, and Restrictive Pulmonary Disorders18.Infectious Pulmonary Disorders and Lung CancerVI.Renal-Urinary System19.Review of Renal System Structure, Development, and Function20.Urinary Tract Disorders21.Kidney DisordersVII.Hematologic and Lymphatic System22.Chapter 22.Review of Hematologic System Development, Structure, and Function 23.Chapter 23.Hematologic and Lymphatic System Disorders SENSATION, MOBILITY, AND REGULATIONVIII.Nervous System24.Review of Nervous System Development, Structure, and Function 25.Central Nervous System Disorders26.Peripheral Nervous System Disorder27.Disorders of the Special Senses28.Mental Health DisordersIX.Musculoskeletal System29.Review of Musculoskeletal Development, Structure, and Function30.Muscle and Tendon Disorders31.Bone and Joint DisordersX.Endocrine System32.Review of Endocrine Structure, Function, and Interactions33.Disorders of the Hypothalamus, Pituitary Glands, and Adrenal Glands34.Disorders of the Thyroid Gland and the Parathyroid Glands35.Glycemic Control and Diabetes MellitusPROTECTION, NUTRITION, AND REPRODUCTIONXI.Disorders of Immunity36.Disorders of Reduced Immune Function37.Hypersensitivity and Autoimmune DisordersXII.Integumentary System38.Review of Integumentary Development, Structure, and Function39.Integumentary System DisorderXIII.Digestive System40.Review of Gastrointestinal Development, Structure, and Function 41.Disorders of the Mouth, Throat, Esophagus, and Stomach42.Disorders of the Small Intestine, Large Intestine, Pancreas, and Hepatobiliary System XIV.Reproductive Systems43.Review of Reproductive System Development, Structure, Function, and Sex Chromosome Abnormalities44.Common Disorders of the Female Reproductive System45.Male Reproductive Disorders46.Sexually Transmitted Infections47. Physiology and Pathophysiology of the Breast

Adjunct Faculty, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland Ohio Formerly Professor, School of Nursing and Health Studies, University of Miami, Coral Gables Florida

• PART I: FOUNDATIONAL PHYSIOLOGIC CONCEPTSI.The Cell1.Cellular Biology, Regulation, and Control Mechanisms2.Cellular and Tissue Physiology3.Bioenergetics and Body Metabolism4.Body Fluid HomeostasisII.Genetics and Genomics5.Basic Genetics6.Patterns of Inheritance, Mitochondrial Inheritance, Epigeneticand Selected Associated DisordersIII.Inflammation, Immunity, Infection, and Cancer Biology7.Innate Immunity and Inflammation8.Adaptive Immunity9.Infectious Processes and Body Responses10.Abnormal Cell Growth and Cancer BiologyPART II: PATHOPHYSIOLOGY OF DISORDERS WITHIN SPECIFIC BODY SYSTEMSOXYGENATION AND PERFUSIONIV.Cardiovascular System11.Review of Cardiovascular Development, Structure, and Function 12.Vascular Disorders13.Cardiac Disorders14.Congenital Heart Disease Across the Lifespan15.Shock and Multiple Organ Dysfunction Syndrome V.Pulmonary System16.Review of Pulmonary Structure, Development, and Function 17.Congenital, Obstructive, and Restrictive Pulmonary Disorders18.Infectious Pulmonary Disorders and Lung CancerVI.Renal-Urinary System19.Review of Renal System Structure, Development, and Function20.Urinary Tract Disorders21.Kidney DisordersVII.Hematologic and Lymphatic System22.Chapter 22.Review of Hematologic System Development, Structure, and Function 23.Chapter 23.Hematologic and Lymphatic System Disorders SENSATION, MOBILITY, AND REGULATIONVIII.Nervous System24.Review of Nervous System Development, Structure, and Function 25.Central Nervous System Disorders26.Peripheral Nervous System Disorder27.Disorders of the Special Senses28.Mental Health DisordersIX.Musculoskeletal System29.Review of Musculoskeletal Development, Structure, and Function30.Muscle and Tendon Disorders31.Bone and Joint DisordersX.Endocrine System32.Review of Endocrine Structure, Function, and Interactions33.Disorders of the Hypothalamus, Pituitary Glands, and Adrenal Glands34.Disorders of the Thyroid Gland and the Parathyroid Glands35.Glycemic Control and Diabetes MellitusPROTECTION, NUTRITION, AND REPRODUCTIONXI.Disorders of Immunity36.Disorders of Reduced Immune Function37.Hypersensitivity and Autoimmune DisordersXII.Integumentary System38.Review of Integumentary Development, Structure, and Function39.Integumentary System DisorderXIII.Digestive System40.Review of Gastrointestinal Development, Structure, and Function 41.Disorders of the Mouth, Throat, Esophagus, and Stomach42.Disorders of the Small Intestine, Large Intestine, Pancreas, and Hepatobiliary System XIV.Reproductive Systems43.Review of Reproductive System Development, Structure, Function, and Sex Chromosome Abnormalities44.Common Disorders of the Female Reproductive System45.Male Reproductive Disorders46.Sexually Transmitted Infections47. Physiology and Pathophysiology of the Breast