Origin and Evolution of Viruses

Esteban Domingo studied chemistry and biochemistry at the University of Barcelona, Spain and spent postdoctoral stays at the University of California, Irvine and the University of Zürich. His main interests are the quasispecies structure of RNA viruses and the development of new antiviral strategies. He is presently Professor of Research of the Spanish Research Council (CSIC) at Centro de Biología Molecular "Servero Ochoa" in Madrid.

• 1. Early Replication: Origin and Evolution2. Structure and Evolution of Viroids3. Mutation, Competition and Selection as Measured with Small RNA Molecules4. Viral Quasispecies: Dynamics, Interactions and Pathogenesis5. Comparative Studies of RNA Virus Evolution6. Nucleic Acid Polymerase Fidelity and Viral Population Fitness7. The complex Interactions of Viruses and the RNAi Machinery: A Driving Force in Viral Evolution8. The Role of the APOBEC3 Family of Cytidine Deaminases in Innate Immunity, G-to-A Hypermutation9. Lethal Mutagenesis10. Evolution of dsDNA Tailed Phages11. More about Plant Virus Evolution – Past, Present and Future12. Mutant clouds and bottleneck events in plant virus evolution13. Retrovirus Evolution14. Intra-host dynamics and evolution of HIV Infection15. The Impact of Rapid Evolution of Hepatitis Viruses16. Arbovirus Evolution17. Evolution and Variation of the Parvoviruses18. Genome Diversity and Evolution of Papillomaviruses19. Origin and Evolution of Poxviruses20. Molecular Evolution of the Herpesvirales21. The widespread evolutional significance of viruses

Review of the previous edition:"...this book...is a detailed account of current thinking on virus evolution... Because of the diversity of subjects, this book gives an up to date picture of research in various fields of virology, and helps to tease out connections between these fields. The subjects covered are essential reading for virologists but also have direct relevance for molecular biologists, and indeed any researchers with interests in early evolution... This publication is highly recommended for its breadth of coverage and detailed treatments of the various subjects" --TODAY'S LIFE SCIENCE (February 2001)