Ophthalmic Drug Delivery

Neelesh Kumar Mehra is an Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, India. He has authored more than 140 peer-reviewed publications in high-repute international journals, and has contributed to over 50 book chapters. He holds 4 granted patents and has 5 patent applications filed on manufacturing processes and compositions to improve therapeutic efficacy for drug delivery. He has supervised 5 PhD students and 36 MS students, and is currently guiding 10 PhD and 7 MS students on their dissertations and research projects. His research focuses on the design, development, and evaluation of ophthalmic nanoemulsions, liposomes, lipid-polymer nanoparticles, carbon nanoparticles, and chitosan/PLGA-lipid nanoparticles for drug and biomolecule delivery in biomedical applications.

• 1. Introduction to Ocular Drug Delivery: Core Principles and Fundamental Concepts2. Complex ophthalmic Drug delivery Approaches3. Excipients and polymers in complex ophthalmic products: Formulation science and engineering perspectives4. Fixed-Dose Combination technique in ophthalmic products5. Emerging trends in ophthalmic products: Microneedles, hydrogels, and ocular inserts6. Reverse Engineering strategy in Complex Ophthalmic Product7. Quality by design and Design of Experiments (DOE) in Ophthalmic Product Development: Statistical Approaches and Optimization Strategies8. Translational roadmap for complex ophthalmic products9. Manufacturing Consideration, Scale-Up and Validation in Sterile Ophthalmic Formulation10. Safety Assessment and Toxicological Considerations of Nanocarriers in Ophthalmic Drug Delivery: Risk management, Animal Model and Preclinical Evaluation11. Advanced packaging, container and closure system for complex ophthalmic products12. Role of 3D Printing in Ophthalmic Products13. Stability Studies of Ophthalmic Product14. Regulatory Landscape of Ophthalmic Products