1. Overview of the Visual SystemJ. Fielding Hejtmancik and John M. Nickerson2. Cornea2.a. Overview of the Cornea: Structure, Function, and DevelopmentAllen O. Eghrari, S. Amer Riazuddin and John D. Gottsch2.b. Stem Cells in the CorneaAndrew J. Hertsenberg and James L. Funderburgh2.c. Corneal Development: Different Cells from a Common ProgenitorPeter Y. Lwigale2.d. Corneal Epithelial Wound Healing Chia-Yang Liu and Winston Whey-Yang Kao2.e.i. Corneal Dystrophies: Overview and summaryDaniel Schorderet2.e.ii. Fuchs Corneal DystrophyAllen O. Eghrari, S. Amer Riazuddin and John D. Gottsch2.e.iii. Molecular Pathogensis of Corneal Dystrophies: Schnyder Dystrophy and Granular Corneal Dystrophy 2Eung Kweon Kim, Hun Lee and Seung-il Choi3. Lens3.a. Overview of the LensJ. Fielding Hejtmancik and Alan Shiels3.b. Lens Development and Crystallin Gene ExpressionAles Cvekl, Rebecca McGreal, and Wei Liu3.c. Lens Biology and BiochemistryJ. Fielding Hejtmancik, S. Amer Riazuddin, Rebecca McGreal, Wei Liu, Ales Cvekl, and Alan Shiels3.d. Molecular Genetics of Cataract Alan Shiels and J. Fielding Hejtmancik4. Refraction4.a. RPE and Choroid Mechanisms Underlying Ocular Growth and MyopiaYan Zhang and Christine Wildsoet4.b. Scleral Mechanisms Underlying Ocular Growth and MyopiaRavi Metlapally and Christine F. Wildsoet4.c. Molecular and Biochemical Aspects of the Retina on RefractionRanjay Chakraborty and Machelle T. Pardue4.d. Genetics of Refraction and MyopiaQingjiong Zhang5. Ocular Immunity5.a. Molecular Genetic Advances in UveitisShengping Hou, Aize Kijlstra and Peizeng Yang6. Aqueous Flow and Intraocular Pressure6.a. Intraocular Pressure and the Mechanisms Involved in Resistance the Aqueous Humor Flow in the Trabecular Meshwork Outflow PathwaysErnst R. Tamm, Barbara M. Braunger and Rudolf Fuchshofer6.b. Glaucoma Genes and MechanismsJaney L. Wiggs6.c. Neuroinflammation in Glaucoma and Optic Nerve DamageCaitlin E. Mac Nair and Robert W. Nickells6.d. What Animal Models Can Tell Us about GlaucomaFelix L. Struebing and Eldon E. Geisert7. Retina7.a. Introduction to the RetinaHans E. Grossniklaus, Eldon E. Geisert and John M. Nickerson7.b. Development of the Vertebrate Eye and RetinaDeborah L. Stenkamp7.c. Insights into the Molecular Properties of ABCA4 and its Role in the Visual Cycle and Stargardt DiseaseRobert S. Molday7.d. A History of the Classical Visual CycleCharles B. Wright, T. Michael Redmond and John M Nickerson7.e. A2E and LipofuscinRosalie K. Crouch, Yiannis Koutalos, Masahiro Kono, Kevin Schey and Zsolt Ablonczy 7.f. Cone Health and RetinoidsMasahiro Kono7.g. Retinoid Processing in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelium CulturesMark A. Fields, Hannah E. Bowrey, Jie Gong, Zsolt Ablonczy and Lucian V. Del Priore7.h. Potential Role of Exercise in Retinal HealthMachelle T. Pardue, Micah A. Chrenek, Robin H. Schmidt, John M. Nickerson and Jeffrey H. Boatright7.i. The Biology of RetinoblastomaPia R. Mendoza and Hans E. Grossniklause-chapter: The 11-cis Retinal Origins of Lipofuscin in the RetinaLeopold Adler IV, Nicholas P. Boyer, Chunhe Chen, Zsolt Ablonczy, Rosalie K. Crouch, Yiannis Koutalos