Metabolomics, Metabonomics and Metabolite Profiling

Inbunden, Engelska, 2007

Av William J Griffiths, UK) Griffiths, William J (Swansea University, William J. Griffiths

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The completion of gene sequencing has resulted in an intensified investigation of the proteome and metabolome. Metabolite profiling methods used for disease diagnosis have been expanded with the advent of new technology and are being applied extensively in the quest for the discovery of new markers for diseases. In this comprehensive resource, the Editor draws together experts from the field and provides an insightful introduction into the technology and methodology. Metabolomics, Metabonomics and Metabolite Profiling covers a broad range of topics including:Mass spectrometry and NMR in metabolite profilingCurrent applications of metabolite profiling for disease diagnosisStudies of specific metabolite classesPlant metabolitesMetabolite data miningGlobal systems biologyThis book is a must have, up-to-date, reference which will appeal to academics, students, technicians and professionals working in, or joining this field.

Produktinformation

Utgivningsdatum2007-10-31
Mått156 x 234 x 19 mm
Vikt647 g
FormatInbunden
SpråkEngelska
SerieRSC Biomolecular Sciences
Antal sidor336
FörlagRoyal Society of Chemistry
ISBN9780854042999

Tillhör följande kategorier

Analytisk kemi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik
Biokemisk teknik inom Naturvetenskap och teknik

Robert C Murphy graduated from Massachusetts Institute of Technology with a PhD in chemistry and he is currently a University Distinguished Professor at the University of Colorado. He has worked in the area of mass spectrometry and eicosanoid biochemistry for approximately 40 years with much of his research activities centered on the use of mass spectrometry to studies of arachidonic acid biochemistry and formation of the biologically active leukotriene mediators. His interests also include the structural characterizaton of bioactive lipid products derived from the reaction of reactive oxygen species with cellular lipids. Over 400 peer-reviewed papers in scientific journals and several books concerning mass spectrometry of lipids have been authored by him.

1. Mass Spectrometry for Metabolite Identification;2. 1D and 2D NMR Spectroscopy: from Metabolic Fingerprinting to Profiling;3. Steroids, Sterols and the Nervous System;4. Phospholipid Profiling;5. New Developments in Multi-dimensional Mass Spectrometry-Based Shotgun Lipidomics;6. Neutral Lipidomics and Mass Spectrometry;7. Bioinformatics of Lipids;8. Mass Spectrometry in Glycobiology, JoÒo Rodrigues;9. Matrix Assisted Laser Desorption Ionisation Mass Spectrometric Imaging - Principles and Applications;10. Plant Metabolomics;11. Data Mining for Metabolomics;12. Metabonomics and Global Systems Biology;