Melatonin and Melatonergic Drugs in Clinical Practice

V.Srinivasan Ph.D MAMSSri Sathya Sai Medical Educational and Research Foundation An International Medical Sciences Research Foundation Prasanthi Nilayam, 40-Kovai Thirunagar, Goldwins, KOVAICoimbatore-641014, Tamilnadu, INDIA

• Melatonin Receptors and Their Role in Human Diseases .- Melatonin’s Antioxidant Properties: Molecular Mechanisms .- Past, Present and Future of Melatonin’s Clinical Uses .- Melatonin in Human Cancer: Therapeutic  Possibilities .- Melatonin: Its Microbicidal Properties and Clinical Applications.- Melatonin and the Metabolic Syndrome .- Development of Agonists and Antagonists for Melatonin Receptors .- Multiple Facets of Melatonin in Immunity: Clinical Applications .- Melatonin and Immune Function: Clinical Significance .- Circadian Variation of Immune Mechanisms in Lung Cancer and the Role of Melatonin .-  Melatonin and Melatonergic Drugs for Therapeutic Use in Breast Cancer .- Melatonin and Malaria: Therapeutic Avenues .- Melatonin's role in human reproduction: recent studies .- Melatonin Treatment and Fertility .- Melatonin and Pain: Therapeutic Applications .- Melatonin in Alzheimer’s disease: Focus on Neuroprotective Role .- Melatonin in Parkinson’s disease and its Therapeutic Potential .- Melatonin and Its Agonists in Sleep Disorders .- Agomelatine in Depressive Disorders .- Melatonin in Mood Disorders and Agomelatine’s Antidepressant Efficacy .- The Role of Agomelatine in the Treatment of Anxiety Disorders .-  Melatonin in the Etiology, Pathophysiology, and Management of Schizophrenia .- Neurobiology of Monoaminergic Neurotransmission and Antidepressants .- Melatonergic Drug - Ramelteon and Its Therapeutic Applications in Insomnia .- Melatonin’s Neuroprotective Actions on Hippocampal Neurons .- Jet Lag: Use of Melatonin and Melatonergic Drugs .- Sleep, Melatonin and Circadian Rhythmicity in Attention Deficit Hyperactivity Disorder .- Melatonergic Drugs and Their Therapeutic Use in Nasal Polyposis .- Protective Effects of Exogenous Melatonin Against Methotrexate- Induced Intestinal Injury.

From the book reviews: "A review in 29 chapters of the various proven or possible effects of melatonin on physiological states and diseases. The controversial issues of clinical and therapeutic applications are backed up by many references. For those interested in the possible use of Melatonin in sleep and neurological disorders." (Pediatric Endocrinology Reviews (PER), Vol. 12 (1), September, 2014) "This book reviews melatonin and its therapeutic clinical application in human disorders. ... The book is aimed at a wide audience including students, neurologists, psychiatrists, psychopharmacologists, oncologists, and scientists with an interest in melatonin. ... It would be helpful for those in a variety of disciplines, including students, researchers, and clinicians." (M. Isabel L. Crisostomo, Doody's Book Reviews, June, 2014)