Melatonin and Melatonergic Drugs in Clinical Practice

Dr Srinivasan Venkataramanujam, Ph.D, MAMS (Member, National Academy of Medical Sciences) India Sri Sathya Sai Medical Educational & Research Foundation, Coimbatore, India Professional Experience: (Teaching & research)in Medical Colleges in INDIA Lecturer in Physiology; JJM Medical College (Davangere) From Feb 1970 to August 1970 Tutor- Madurai Medical college , Madurai From September 1970 to 1974 Assistant Professor of Physiology Madurai Medical College , Sept 1974 to Nov 1994. Associate Professor in Physiology Perundurai Medical College , From Nov 1994 to July 1996. Professor of Physiology ,PSG Institute of Medical Sciences Coimbatore, From July 1996to Feb, 2002 Professor of Physiology SRM Medical College , Kancheepuram Dt, From Sept 2008 to 27 Aug 2009. Teaching & Research Experiance in Malaysia Professor Madya in Dept of Physiology ,School of Medical Sciences University Sains Malaysia, Kubang Kerian, KotaBharu, Malaysia From Feb 27 2002 to ^th Sept 2008 ( 6 year , 6 months) Papers presented/published in National & International Journals : 110. (40 with International collaboration ). Chapters written In Books published by International Medical Publishers : 6.

• Melatonin Receptors and Their Role in Human Diseases .- Melatonin’s Antioxidant Properties: Molecular Mechanisms .- Past, Present and Future of Melatonin’s Clinical Uses .- Melatonin in Human Cancer: Therapeutic  Possibilities .- Melatonin: Its Microbicidal Properties and Clinical Applications.- Melatonin and the Metabolic Syndrome .- Development of Agonists and Antagonists for Melatonin Receptors .- Multiple Facets of Melatonin in Immunity: Clinical Applications .- Melatonin and Immune Function: Clinical Significance .- Circadian Variation of Immune Mechanisms in Lung Cancer and the Role of Melatonin .-  Melatonin and Melatonergic Drugs for Therapeutic Use in Breast Cancer .- Melatonin and Malaria: Therapeutic Avenues .- Melatonin's role in human reproduction: recent studies .- Melatonin Treatment and Fertility .- Melatonin and Pain: Therapeutic Applications .- Melatonin in Alzheimer’s disease: Focus on Neuroprotective Role .- Melatonin in Parkinson’s disease and its Therapeutic Potential .- Melatonin and Its Agonists in Sleep Disorders .- Agomelatine in Depressive Disorders .- Melatonin in Mood Disorders and Agomelatine’s Antidepressant Efficacy .- The Role of Agomelatine in the Treatment of Anxiety Disorders .-  Melatonin in the Etiology, Pathophysiology, and Management of Schizophrenia .- Neurobiology of Monoaminergic Neurotransmission and Antidepressants .- Melatonergic Drug - Ramelteon and Its Therapeutic Applications in Insomnia .- Melatonin’s Neuroprotective Actions on Hippocampal Neurons .- Jet Lag: Use of Melatonin and Melatonergic Drugs .- Sleep, Melatonin and Circadian Rhythmicity in Attention Deficit Hyperactivity Disorder .- Melatonergic Drugs and Their Therapeutic Use in Nasal Polyposis .- Protective Effects of Exogenous Melatonin Against Methotrexate- Induced Intestinal Injury.

From the book reviews: "A review in 29 chapters of the various proven or possible effects of melatonin on physiological states and diseases. The controversial issues of clinical and therapeutic applications are backed up by many references. For those interested in the possible use of Melatonin in sleep and neurological disorders." (Pediatric Endocrinology Reviews (PER), Vol. 12 (1), September, 2014) "This book reviews melatonin and its therapeutic clinical application in human disorders. ... The book is aimed at a wide audience including students, neurologists, psychiatrists, psychopharmacologists, oncologists, and scientists with an interest in melatonin. ... It would be helpful for those in a variety of disciplines, including students, researchers, and clinicians." (M. Isabel L. Crisostomo, Doody's Book Reviews, June, 2014)