Brian S Boxer Wachler MDBoxer Wachler Vision Institute, Beverly Hills, California, USA Maxine LipnerMedical Writer, Nyack, New York, USA

• Introduction: The Holcomb C3-R® at the Starting GateGoing for the Gold: Steven Holcomb’s Olympic Story and Putting C3-R® on the MapHistory of Crosslinking in Industry, Medicine, and AgingBasic Science of Corneal CrosslinkingFirst Patient Results: The Dresden ExperienceDevelopment and Naming of Holcomb C3-R®First Presentation of Results of Holcomb C3-R® and Holcomb C3-R® Combined with Intacs®Why it’s Not Glamorous to be a Pioneer in the BeginningTechniques of Holcomb C3-R® Crosslinking System (Epithelium-On) and CXL (Epithelium-Off)Complications of CXL (Epithelium Off)Results and Complications of Holcomb C3-R® (Epithelium On)Combining the Holcomb C3-R® Crosslinking System with Intacs®Use of Holcomb C3-R® for Improving Stability in Radial Keratotomy PatientsHolcomb C3-R® with PRKUse of Crosslinking for Corneal Infections and Autoimmune Corneal MeltsUse of the Holcomb C3-R® for Trampolining Corneas after LASIKCombining use of the Holcomb C3-R® with Conductive Keratoplasty and Phakic ICLsLooking into the Crystal Ball: What Lies Ahead for Corneal Collagen Crosslinking

Brian S Boxer Wachler MDBoxer Wachler Vision Institute, Beverly Hills, California, USA Maxine LipnerMedical Writer, Nyack, New York, USA

• Introduction: The Holcomb C3-R® at the Starting GateGoing for the Gold: Steven Holcomb’s Olympic Story and Putting C3-R® on the MapHistory of Crosslinking in Industry, Medicine, and AgingBasic Science of Corneal CrosslinkingFirst Patient Results: The Dresden ExperienceDevelopment and Naming of Holcomb C3-R®First Presentation of Results of Holcomb C3-R® and Holcomb C3-R® Combined with Intacs®Why it’s Not Glamorous to be a Pioneer in the BeginningTechniques of Holcomb C3-R® Crosslinking System (Epithelium-On) and CXL (Epithelium-Off)Complications of CXL (Epithelium Off)Results and Complications of Holcomb C3-R® (Epithelium On)Combining the Holcomb C3-R® Crosslinking System with Intacs®Use of Holcomb C3-R® for Improving Stability in Radial Keratotomy PatientsHolcomb C3-R® with PRKUse of Crosslinking for Corneal Infections and Autoimmune Corneal MeltsUse of the Holcomb C3-R® for Trampolining Corneas after LASIKCombining use of the Holcomb C3-R® with Conductive Keratoplasty and Phakic ICLsLooking into the Crystal Ball: What Lies Ahead for Corneal Collagen Crosslinking

Brian S Boxer Wachler MDBoxer Wachler Vision Institute, Beverly Hills, California, USA Maxine LipnerMedical Writer, Nyack, New York, USA

• Introduction: The Holcomb C3-R® at the Starting GateGoing for the Gold: Steven Holcomb’s Olympic Story and Putting C3-R® on the MapHistory of Crosslinking in Industry, Medicine, and AgingBasic Science of Corneal CrosslinkingFirst Patient Results: The Dresden ExperienceDevelopment and Naming of Holcomb C3-R®First Presentation of Results of Holcomb C3-R® and Holcomb C3-R® Combined with Intacs®Why it’s Not Glamorous to be a Pioneer in the BeginningTechniques of Holcomb C3-R® Crosslinking System (Epithelium-On) and CXL (Epithelium-Off)Complications of CXL (Epithelium Off)Results and Complications of Holcomb C3-R® (Epithelium On)Combining the Holcomb C3-R® Crosslinking System with Intacs®Use of Holcomb C3-R® for Improving Stability in Radial Keratotomy PatientsHolcomb C3-R® with PRKUse of Crosslinking for Corneal Infections and Autoimmune Corneal MeltsUse of the Holcomb C3-R® for Trampolining Corneas after LASIKCombining use of the Holcomb C3-R® with Conductive Keratoplasty and Phakic ICLsLooking into the Crystal Ball: What Lies Ahead for Corneal Collagen Crosslinking