Kanu Chatterjee MBBS FRCP (London & Edin) FCCP FACC MACPProfessor Mark Anderson MD PhDProfessor of Medicine & Physiology, Head, Dept of Internal Medicine; Director of Cardiovascular Research Centre Donald Heistad MDZahn Professor of Cardiology (Internal Medicine & Pharmacology) Richard E Kerber MDProfessor All at The Carver College of Medicine, University of Iowa, USA