Lipid Mediators and Their Metabolism in the Brain

Dr. Akhlaq A. Farooqui is a leader in the field of signal transduction, brain phospholipases A2, bioactive ether lipid metabolism, polyunsaturated fatty acid metabolism, glycerophospholipid-, sphingolipid-, and cholesterol-derived lipid mediators, and glutamate-induced neurotoxicity. Dr. Farooqui has authored six monographs: Glycerophospholipids in Brain: Phospholipase A2 in Neurological Disorders (2007); Neurochemical Aspects of Excitotoxicity (2008); Metabolism and Functions of Bioactive Ether Lipids in Brain (2008); and Hot Topics in Neural Membrane Lipidology (2009); Beneficial Effects of Fish Oil in Human Brain (2009); and Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases (2010). All monographs are published by Springer, New York. In addition, Dr. Akhlaq A. Farooqui has edited 4 books (Biogenic Amines: Pharmacological, Neurochemical and Molecular Aspects in the CNS (2010) Nova Science Publisher, Hauppauge, N.Y, Molecular Aspects of Neurodegeneration and Neuroprotection, Bentham Science Publishers Ltd (2011); Phytotherapeutics and Human Health: Molecular and pharmacological Aspects, Nova Science Publisher, Hauppauge, N.Y In Press (2011) and Molecular Aspects of Oxidative Stress on Cell Signaling in Vertebrates and Invertebrates, Wiley Blackwell Publishing Company, New York in press, 2011).

• Chapter 1. Metabolism and roles of eicosanoids in brain.- Chapter 2. Recent Developments on the neurochemistry of docosanoids.- Chapter 3. Metabolism, roles, and involvement of lyso-glycerophospholipids in neurological disorders.- Chapter 4. Platelet activating factor in brain: its metabolism, roles and involvement in neurological disorders.- Chapter 5. Cannabinoids in the brain: their metabolism, roles, and involvement in neurological disorders.- Chapter 6. Neurochemical aspects of 4-hydroxynonenal.- Chapter 7. Isoprostanes and other non-enzymic polyunsaturated fatty acid-derived lipid mediators in the brain.- Chapter 8. Ceramide and ceramide 1-phosphate in the brain.- Chapter 9. Sphingosine and sphingosine 1 phosphate in brain.- Chapter 10. Cholesterol and hydroxycholesterol in the brain.- Chapter 11. Perspective and direction for future research on lipid mediators.