Ketogenic Diet and Metabolic Therapies

Susan A. MasinoVernon D. Roosa Professor of Applied Science, Trinity College

• 1. General overview/introduction by co-editors, with a historical perspective Section I. Ketogenic Diet for Epilepsy in the Clinic 2. Overview: Ketogenic Diets and Pediatric Epilepsy: An Update3. 'Alternative' Ketogenic Diets4. Ketogenic Diet Therapies in Adults: History, Demand, and Results5. How Do You Implement the Diet?6. Glut1 Deficiency Syndrome and the Ketogenic Dietary Therapies7. Ketogenic Diet in Established Epilepsy Indications8. Ketogenic Diet for Other Epilepsies9. The Ketogenic Diets in Idiopathic Generalized Epilepsy Syndromes10. Ketogenic Diet Therapy for Infants with Pharmacoresistant Epilepsy and/or Metabolic Disease11. Ketogenic Diet in Status Epilepticus12. Preventing Side Effects and Diet Discontinuation Section II. Ketogenic Diet: Emerging Clinical Applications and Future Potential 13. Overview: Expanded Uses of Ketogenic Therapies14. Metabolism-Based Treatments for Managing Cancer: Scientific Rationale15. Ketogenic Diet as Adjunctive Therapy for Malignant Brain Cancer16. Ketogenic Diet, Social Behavior, and Autism: Insights from Animal Models17. Ketotherapeutics to Rescue Brain Energy Deficits: An Emerging Strategy to Delay Cognitive Decline in Alzheimer's Disease18. Ketogenic Diet and Ketones for Improving Neurological Outcomes after Acute Neurotrauma19. Ketogenic Diets and Neuroinflammation20. The Ketogenic Diet in the Treatment of Schizophrenia21. The Ketogenic Diet and the Gut Microbiome Section III. Ketogenic Diet in the Laboratory 22. Overview of Ketogenic Diet in the Laboratory: Progress on Models and Mechanisms23. Ketogenic Diet and PPARy24. Ketogenic Diet and Adenosine in Epilepsy - Models and Mechanisms25. Ketogenic Diet and Epigenetic Mechanisms of Epileptogenesis26. Ketogenic Diet, Aging, and Neurodegeneration27. Metabolic Seizure Resistance via BAD and KATP Channels28. Lactate Dehydrogenase: a Novel Metabolic Target29. Effects of the Ketogenic Diet on the Blood-Brain Barrier30. Metabolic and Redox Alterations by Ketogenic Diets31. Nicotinamide Adenine Dinucleotide as a Central Mediator of the Ketogenic therapy Section IV. Ketone-Based Metabolism: General Health and Metabolic Alternatives 32. Overview of Ketone-Based Metabolism: General Health and Metabolic Alternatives33. Ketone Supplementation for Health and Disease34. Neuroprotective and Behavioral Benefits of Exogenous Ketone Supplementation-evoked Ketosis35. Amino Acids in the Treatment of Neurological Disorders36. Identifying the Molecular Mechanism of the MCT (Ketogenic) Diet37. Triheptanoin in Epilepsy and Beyond38. Anti-seizure and Anti-epileptic Effects of Glycolysis Inhibition with 2-Deoxyglucose39. Low Carbohydrate, Ketogenic Diets for the Treatment of Type 2 Diabetes and Obesity40. Intermittent Exogenous Ketosis for Athletic Performance, Recovery and Adaptation41. Advancing the Awareness and Application of Metabolic and Ketogenic Therapies Globally and Offering Hope