Del 10 - Metal Ions in Life Sciences

Interplay between Metal Ions and Nucleic Acids

Inbunden, Engelska, 2012

Av Astrid Sigel, Helmut Sigel, Roland KO Sigel, Roland Ko Sigel

2 799 kr

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Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.

Produktinformation

Utgivningsdatum2012-01-03
Mått155 x 235 x 26 mm
Vikt746 g
FormatInbunden
SpråkEngelska
SerieMetal Ions in Life Sciences
Antal sidor354
Upplaga2012
FörlagSpringer
ISBN9789400721715

Tillhör följande kategorier

1. Characterization of Metal Ion-Nucleic Acid Interactions in Solution. - 2. Nucleic Acid-Metal Ion Interactions in the Solid State. - 3. Metal Ion-Promoted Conformational Changes of Oligonucleotides. - 4. G-Quadruplexes and Metal Ions. - 5. Metal Ion-Mediated DNA-Protein Interactions. - 6. Spectroscopic Investigations of Lanthanide Ion Binding to Nucleic Acids. - 7. Oxidative DNA Damage Mediated by Transition Metal Ions and Their Complexes. - 8. Metal Ion-Dependent DNAzymes and Their Applications as Biosensors. - 9. Enantioselective Catalysis at the DNA Scaffold. - 10. Alternative DNA Base Pairing through Metal Coordination. - 11. Metal-Mediated Base Pairs in Nucleic Acids with Purine- and Pyrimidine-Derived Nucleosides. - 12. Metal Complex Derivatives of Peptide Nucleic Acids.

From the reviews:“Bioinorganic chemistry is an exciting branch of chemistry with applications in new materials (including sensors and tissues), health (diagnosis and therapy), energy supplies (generation and storage), biological function, evolution, and beyond. The Sigel volumes are always a reliable way of keeping abreast of this rapidly expanding field. This one is no exception. ... This book is a good read and all bioinorganic chemists might wish it was on their shelves—not only for research, but as a resource for undergraduate teaching” (Peter J. Sadler, Angewandte Chemie International Edition, Vol. 51, 2012)“‘Interplay between Metal Ions and Nucleic Acids’ … is for the entire community of researchers interested in metal-nucleic acid interactions. Its contents are highly topical, as they cover numerous relevant areas of a research that faces rapid growth. Reading this volume is a ‘must’ for scientists active in this field, and the editors should be congratulated on the fine selection of chapters and authors. … volume10 of MILS is among the very best books on this subject that have appeared in recent years!” (Bernhard Lippert, Inorganica Chimica Acta,Vol. 394, January, 2013)"This book will be an excellent companion to postgraduate students and established researchers interested in the essential role that metal ions play in the structure and function of nucleic acids. In addition, this volume will be of interest to scientists working towards the use of nucleic acids for sensing and catalytic applications, as well as for the development of novel nanomaterials." (Ramon Vilar, Transition Metal Chemistry, Vol. 37, 2012)