This book constitutes the refereed proceedings of the 51st Annual Conference of the Southern African Computer Lecturers' Association, SACLA 2022, held in Cape Town, South Africa, during July 21–22, 2022.The 10 full papers were included in this book were carefully reviewed and selected from 31 submissions. They were organized in topical sections as follows: ​curriculum; assessment; teaching in context; innovative teaching; and pandemic pedagogy.