History of Genomics across Species, Communities and Projects

Inbunden, Engelska, 2023

Av Miguel García-Sancho, James Lowe, Miguel Garcia-Sancho

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They show how practices such as genome mapping, sequence assembly and annotation are as essential as DNA sequencing in the history of genomics, and argue that existing depictions of genomics are too closely associated with the Human Genome Project.

Produktinformation

Utgivningsdatum2023-04-01
Mått148 x 210 x 28 mm
Vikt650 g
FormatInbunden
SpråkEngelska
SerieMedicine and Biomedical Sciences in Modern History
Antal sidor380
FörlagSpringer International Publishing AG
ISBN9783031061295

Tillhör följande kategorier

Naturvetenskapens historia inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik
Medicinhistoria inom Medicin
Historia inom Historia och arkeologi
Agronomi och lantbruk inom Naturvetenskap och teknik

Miguel García-Sancho is a Senior Lecturer at the University of Edinburgh in the UK. He led the project ‘TRANSGENE: Medical Translation in the History of Modern Genomics’, with funding from the European Research Council.James Lowe is a Senior Research Fellow at the University of Edinburgh in the UK. He is a historian and philosopher of biology who worked on the European Research Council-funded project ‘TRANSGENE: Medical Translation in the History of Modern Genomics’.

Chapter 1. Introduction.- Part I. The Diversity of Genomics.- Chapter 2. Distributed and Concentrated Strategies in the Sequencing of the Yeast Genome.- Chapter 3. The Human Genome Project(s).- Part II. Communities and Reference Genomes.- Chapter 4. The Funnelling Effect of the Sanger Institute.- Chapter 5. The Pig Community and Their Reference Genome.- Part III. Contextualising and Enhancing Reference Genomes.- Chapter 6. Making Reference Genomes Useful: Annotation.- Chapter 7. Improving and Going Beyond Reference Genomes.- Chapter 8. Conclusion.

“These new accounts of various genome projects, based on new interviews and archival work, should stand in their own right as important contributions to the history of sequencing. García-Sancho and Lowe frame these stories as contributions to an explicitly revisionist history of genomics. … the book’s revisionist argument hinges on an expansive definition of genomics that seeks to include a wide range of practices related to medicine and agriculture.” (Hallam Stevens, Journal of the History of Biology, Vol. 57 (1), 2024)