Diet, Nutrition, and Fetal Programming

Dr Rajkumar 'Siraj' RajendramKing's College LondonDepartment of Nutrition and DieteticsNutritional Sciences DivisionSchool of Biomedical & Health SciencesLondon, UKVictor R. Preedy, BSc, PhD, DScKing's College LondonDepartment of Nutrition and DieteticsNutritional Sciences DivisionSchool of Biomedical & Health SciencesLondon, UKVinood B. Patel, BSc, PhDUniversity of WestminsterFaculty of Science & TechnologyDepartment of Biomedical SciencesLondon, UK

• Part I: Maternal Diet, Health and the Fetus: General Considerations.- Prenatal Maternal Stress in the Context: Maternal Stress Physiology, Immunology, Neuroendocrinology, Nutrition and Infant Development.- The Effects of Parental Diet on Fetal Programming of Stress-Related Brain Regions and Behaviors: Implications for Development of Neuropsychiatric Disorders.- Maternal Nutrition and Cognition.- Maternal Characteristics predisposing to Fetal Growth Restriction.- Maternal Insulin Sensitivity and Fetal Brain Activity.- Part II: Maternal Undernutrition and Protein Restriction: Effects on Fetus.- Dietary Restriction and the Endocrine Profiles in Offspring and Adults.- Maternal Undernutrition and Visceral Adiposity.- Maternal Undernutrition and Long-term Effects on Hepatic Function.- Maternal Protein Restriction and its Effects on Heart.- Effects of Maternal Protein Restriction on Nephrogenesis and Adult and Aging Kidney.- Maternal Protein Restriction and Effects on Behavior and Memory in Offspring.- Part III: Effects of Obesity, High Fat Diet and Junk Food on Fetal Outcomes.- Trends in Obesity and Implications for the Fetus.- Maternal Obesity and Implications for Fetal Programming.- Ethnicity, Obesity, and Pregnancy Outcomes on Fetal Programming.- Obesogenic Programming of Foetal Hepatic Metabolism by MircoRNAs.- Impacts of Maternal High Fat Diet on Stree-related Behavior and the Endocrine Response to Stress in Offspring.- Materna; Junk Food Diets: The Effects on Offspring Fat Mass and Food Preferences.- Part IV: Specific Dietary Components.- Maternal Fish Intake During Pregnancy and Effects on the Offspring.- Maternal Fish Oil Intake and Insulin Resistance in the Offspring.- Maternal n-3 Fatty Acids and Blood Pressure in Children.- Maternal Folate, Methyl Donors, One Carbon Metabolism, Vitamin B12 and Choline in Fetal Programming.- Maternal Taurine Supplementation Prevents Misprogramming.- Fetal Programming: Maternal Diets, Tryptophan and Postnatal Development.- Intrauterine Programming and Effects of Caffeine.- Part V: International Aspects and Policies.- Famines, Pregnancy and Effect on the Adults.- Maternal Malnutrition, Fetal Programming, Outcomes and Strategies in India.- Maternal Nutritional Factors Dictating Birth Weights: African Perspectives.- Maternal Nutrition in Ireland: Issues of Public Concern.- Maternal Malnutrition, Fetal Programming, Outcomes, and Implications of Environmental Factors in Japan.- Part VI: Effects of Fetal Programming in Childhood and Adulthood.- Growth Criteria and Predictors of Fetal Programming.- Effects of Fetal Programming on Metabolic Syndrome.- Fetal Programming of Food Preferences and Feeding Behavior.- Effects of Fetal Programming on Osteoporosis.- Childhood Sleep after Fetal Growth Restriction.- Part VII: Mechanisms of Programming.- Biomarkers of Abnormal Birth Weight in Pregnancy.- Mechanisms of Programming: Pancreatic Islets and Fetal Programming.- Pancratic GABA and Serotonin Actions in the Pancreas and Fetal Programming of Metabolism.- Maternal Malnutrition, Glucocorticoids and Fetal Programming: A Role for Placental 11β-hydroxysteroid dehydrogenase Type 2.- High-fat Diet and Fetal Programming: Use of p66Shc Knockouts and Implications for Human Kind.- Fetal Programming of Telomere Biology: Role of Maternal Nutrition, Obstetric Risk Factors and Suboptimal Birth Outcomes. Part VIII: Resources.- Current Research and Recommended Resources on Fetal Nutrition.

“Nutritionists, dietitians, public health scientists, medical physicians including obstetricians and pediatricians, epidemiologists, and policy makers will benefit from this book. Developmental origins researchers, both in the areas of basic and clinical sciences, also will find it useful. It serves as both an introductory review and a comprehensive book on the topic of fetal programming. …This book will provide developmental origins researchers with up-to-date information.” (Jami L. Josefson, Doody's Book Reviews, February, 2018)