Computational Systems Pharmacology and Toxicology

Dr Dale E. Johnson is currently an Adjunct Professor in Molecular Toxicology at UC Berkeley and an Adjunct Professor in Environmental Health Sciences at the University of Michigan. He teaches computational toxicology, drug discovery & development, and lectures in pharmacogenomics. He is also President and CEO of Emiliem, Inc. and CEO of Elara Bioscience LLC, a software company. He also consults for biopharmaceutical companies and investment firms. Dr Johnson has over 30 years’ experience as a research and development scientist, manager, executive, and entrepreneur in the biopharmaceutical field working in large pharmaceutical and biotech companies and several start-ups. Prior to Emiliem, he served as VP Drug Assessment & Development and VP Preclinical Development at Chiron Corporation and previously worked at Hoechst-Roussel Pharmaceuticals, International Research and Development Corp., Medical Research Division of American Cyanamid, Eos Biotechnology and Ddplatform. Dr Rudy J. Richardson is currently the Dow Professor of Toxicology at the University of Michigan. He also holds a joint appointment in the Neurology Department. Sabbatical leaves at Warner-Lambert/Parke-Davis (now Pfizer) in Ann Arbor and the University of Padua in Italy. Dr Richardson has served several times as the Director of the Toxicology Program, and currently he serves as Graduate Chair of the EHS Department. His research interests include computational toxicology, biomarkers and biosensors of exposure and disease, mechanisms of neurodegenerative disease, chemistry and toxicology of organophosphorus and organic nitro compounds, and interactions of toxicants with target macromolecules.

• Systems Biology Approaches in Pharmacology and Toxicology;Databases Facilitating Systems Biology Approaches in Toxicology;Tools for Green Molecular Design to Reduce Toxicological Risk;Linking Environmental Exposure to Toxicity;Linking Drug or Phytochemical Exposure to Toxicity;Chemical Similarity, Shape Matching and QSAR;In silico Chemical-Protein Docking and Molecular Dynamics;Computational Tools for Chemical Toxicity Testing and Risk Assessment Under the Framework of Adverse Outcome Pathways;In silico Toxicology: An Overview of Toxicity Databases, Prediction Methodologies and Expert Review;Data Sources for Herbal and Traditional Medicines;Network Pharmacology Research Approaches for Chinese Herbal Medicines;Chemical-Disease Category Linkage (CDCL): Computational Methods Linking Traditional Chinese Medicines and Western Therapeutics;Educational Programs for Computational Toxicology and Pharmacology