Complex Ophthalmic Dosage Forms: Advances in Biomedical Applications and Future Perspectives

Dr. Neelesh Kumar Mehra is working in the Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He earned PhD from Dr. H.S. Gour University, Sagar and PostDoc from Irma Lerma Rangel College of Pharmacy, Texas A & M Health Science Centre, Kingsville, TX, USA. He served as Manager in Product Development, Sentiss Research Centre, Sentiss Pharma Pvt Ltd. Gurgaon for development, scale-up and technology transfer of complex ophthalmic, inhalation and optic pharmaceutical products. He received ‘TEAM AWARD’ for successful commercialisation of Ophthalmic Suspension product. He has authored more than 130 peer-reviewed publications in high repute International Journals, and >40 book chapter contributions. He has 04 granted and 04 filed patent on manufacturing process and composition to improved therapeutic efficacy for topical delivery. He has guided 04 PhD Student and 36 MS Students and currently guiding 11 PhD and 05 M.S. students for their dissertations/research projects. He has received numerous outstanding awards including Young Scientist and Team Awards for their research output. He is a peer reviewer of various international Journals and publishers.He recently published edited book on Multifunctional nanocarriers, Biopharmaceutical and nanotechnology. He has rich research and teaching experience in the formulation and development of complex, innovative ophthalmic and injectable biopharmaceutical products including micro- and nanotechnologies for regulated market and so on.According to announcement by the Stanford University Scientists based on the database and basis of standardized citation indicators, Dr. Mehra name is included in top 2% scientists in the world in the area of Pharmacology and Pharmacy, consecutively for 3 years.

• CHAPTER 1.  Ocular drug delivery: introduction and fundamental concept.- CHAPTER 2. Eye: anatomy, physiology and disease.- CHAPTER 3. Drug delivery to the anterior segment of eye.- CHAPTER 4. Drug delivery to the posterior segment of eye.- CHAPTER 5. Fixed-dose combination approach in therapeutic delivery to the eye.- CHAPTER 6. Role of preservatives in ophthalmic products.- CHAPTER 7. Reverse engineering in complex/combination ophthalmic product.- CHAPTER 8. Role of quality by design (qbd) in ophthalmic products.- CHAPTER 9. Advances and opportunities of the novel functional nanocarriers.- CHAPTER 10. Safety and toxicities of nanocarriers in ophthalmic drug delivery system.- CHAPTER 11. Validation in sterile ophthalmic formulation.- CHAPTER 12. Packaging, container and closure of ophthalmic products.- CHAPTER 13. Regulatory perspectives in ophthalmic products.- CHAPTER 14. Polymeric microsponges for drug delivery to ocular candidiasis infections: preclinical and clinical evidences.