Randall H. Morse's interest in chromatin originated with an undergraduate course in molecular genetics in 1975. After finishing his graduate studies in biophysical chemistry at Caltech, Dr. Morse worked as a postdoctoral fellow at Columbia University and the National Institutes of Health. He continued to conduct research on chromatin and transcription in his own lab at the Wadsworth Center in Albany, New York. Additionally, he has taught chromatin structure and function to graduate students in the Department of Biomedical Sciences at the University at Albany School of Public Health since 1994. Dr. Morse has contributed his expertise and research on chromatin structure and function to numerous conferences. Furthermore, he has written articles and reviews on this subject and has received several competitive grants to fund his research.

• Part I. Chromatin structure1. Early history2. Unveiling the nucleosome3. Chromatin folding4. Nucleosome positioning5. Histone variantsPart II. Chromatin function6. Chromatin remodeling7. Chromatin modifications8. Chromatin and transcription

"...explores the complexities of chromatin structure and its sophisticated mechanisms of modulation.... [It] takes an explicitly historical approach to describing how available knowledge and technology interact to both govern as well as limit the course of scientific advancements in biomolecular research. It represents an ideal vehicle for teaching students and other trainees about both the nature of chromatin and the biomolecular research enterprise, as well as an informative and pleasant read for the expert investigator.... A moderate number of informative figures supplement the text, while each chapter cites a rich array of source material.... Among this array of choices, this book stands out by virtue of its attractive, and well-executed, blending of scientific knowledge with human and technical science history. [A]n exceptionally readable book whose contents should be accessible to a wide range of potential readers." --©Doody’s Review Service, 2024, Peter J. Kennelly, PhD (Virginia Tech)

Randall H. Morse's interest in chromatin originated with an undergraduate course in molecular genetics in 1975. After finishing his graduate studies in biophysical chemistry at Caltech, Dr. Morse worked as a postdoctoral fellow at Columbia University and the National Institutes of Health. He continued to conduct research on chromatin and transcription in his own lab at the Wadsworth Center in Albany, New York. Additionally, he has taught chromatin structure and function to graduate students in the Department of Biomedical Sciences at the University at Albany School of Public Health since 1994. Dr. Morse has contributed his expertise and research on chromatin structure and function to numerous conferences. Furthermore, he has written articles and reviews on this subject and has received several competitive grants to fund his research.

• Part I. Chromatin structure1. Early history2. Unveiling the nucleosome3. Chromatin folding4. Nucleosome positioning5. Histone variantsPart II. Chromatin function6. Chromatin remodeling7. Chromatin modifications8. Chromatin and transcription

"...explores the complexities of chromatin structure and its sophisticated mechanisms of modulation.... [It] takes an explicitly historical approach to describing how available knowledge and technology interact to both govern as well as limit the course of scientific advancements in biomolecular research. It represents an ideal vehicle for teaching students and other trainees about both the nature of chromatin and the biomolecular research enterprise, as well as an informative and pleasant read for the expert investigator.... A moderate number of informative figures supplement the text, while each chapter cites a rich array of source material.... Among this array of choices, this book stands out by virtue of its attractive, and well-executed, blending of scientific knowledge with human and technical science history. [A]n exceptionally readable book whose contents should be accessible to a wide range of potential readers." --©Doody’s Review Service, 2024, Peter J. Kennelly, PhD (Virginia Tech)

Randall H. Morse's interest in chromatin originated with an undergraduate course in molecular genetics in 1975. After finishing his graduate studies in biophysical chemistry at Caltech, Dr. Morse worked as a postdoctoral fellow at Columbia University and the National Institutes of Health. He continued to conduct research on chromatin and transcription in his own lab at the Wadsworth Center in Albany, New York. Additionally, he has taught chromatin structure and function to graduate students in the Department of Biomedical Sciences at the University at Albany School of Public Health since 1994. Dr. Morse has contributed his expertise and research on chromatin structure and function to numerous conferences. Furthermore, he has written articles and reviews on this subject and has received several competitive grants to fund his research.

• Part I. Chromatin structure1. Early history2. Unveiling the nucleosome3. Chromatin folding4. Nucleosome positioning5. Histone variantsPart II. Chromatin function6. Chromatin remodeling7. Chromatin modifications8. Chromatin and transcription

"...explores the complexities of chromatin structure and its sophisticated mechanisms of modulation.... [It] takes an explicitly historical approach to describing how available knowledge and technology interact to both govern as well as limit the course of scientific advancements in biomolecular research. It represents an ideal vehicle for teaching students and other trainees about both the nature of chromatin and the biomolecular research enterprise, as well as an informative and pleasant read for the expert investigator.... A moderate number of informative figures supplement the text, while each chapter cites a rich array of source material.... Among this array of choices, this book stands out by virtue of its attractive, and well-executed, blending of scientific knowledge with human and technical science history. [A]n exceptionally readable book whose contents should be accessible to a wide range of potential readers." --©Doody’s Review Service, 2024, Peter J. Kennelly, PhD (Virginia Tech)