Carbohydrate Chemistry

Dr Yves Queneau, Research Director at CNRS, is Head of the Organic and Bioorganic Chemistry Laboratory at INSA Lyon, Deputy-Director of the “Institut de Chimie et Biochimie Moléculaires et Supramoléculaires” (ICBMS), University of Lyon, France and Honorary Professor at the University of Hull, UK. After his doctorate on aqueous Diels-Alder reactions involving glycodienes under the supervision of Professor André Lubineau (Orsay, 1988) he was appointed as CNRS fellow and worked on cycloaddition reactions towards complex sugars. He then spent one year in 1992 in Professor Samuel J. Danishefsky’s group in Memorial Sloan Kettering Cancer Center in New York, USA. He later moved to Lyon in a mixed CNRS-industrial research facility dedicated to sucrose chemistry (1995-2003) before joining its present position where he develops his research in organic and biological chemistry with a particular interest for the use of carbohydrates as renewable raw materials.

• Preface;Design and synthesis of glycomimetics;Pyranose glycals in the generation of skeletal diversity;Recent developments in the stereoselective synthesis of deoxy glycosides;Lewis acid promoted anomerisation: recent developments and applications;Progress in the synthesis of mycothiol, its biosynthetic precursors and analogues;Synthetic receptors for molecular recognition of carbohydrates;Contribution of carbohydrate chemistry to assessment of the biological role of natural alpha-glycosides;Carbohydrate-carbohydrate interation: from hypothesis to confirmation