Breathborne Biomarkers and the Human Volatilome

Nyhet

From Chemistry and Biology to Technology and Applications

Häftad, Engelska, 2026

AvJonathan Beauchamp,Cristina Davis,Joachim Pleil

2 489 kr

Kommande

Breathborne Biomarkers and the Human Volatilome: From Chemistry and Biology to Technology and Applications, Third Edition, is the definitive resource for researchers, clinicians, and industry professionals interested in the power of breath analysis for health and disease monitoring. This comprehensive guide covers the latest scientific discoveries, innovative detection technologies, and practical applications of volatile organic compounds (VOCs) in breath, offering valuable insights into how these biomarkers can be used for early diagnosis, personalized medicine, and environmental exposure assessment. Whether you are developing new diagnostic tools or conducting advanced research, this book provides the essential knowledge needed to unlock the full potential of breath analysis. With in-depth coverage of biomarkers, data analytics, and cutting-edge sensor technologies, this edition bridges fundamental science with real-world applications. It is an ideal reference for scientists, healthcare professionals, and industry innovators aiming to stay at the forefront of this rapidly evolving field. By providing clear explanations, current perspectives, and future directions, Breathborne Biomarkers and the Human Volatilome: From Chemistry and Biology to Technology and Applications, Third Edition empowers readers to harness the power of breath for improved health outcomes and environmental monitoring-making it an indispensable tool in modern biomedical science.

Provides an extensive overview of established biomarkers, cutting-edge detection tools, key disease targets, and specific real-world applications
Covers data analytics and study design in detail, offering a complete understanding of how to conduct and interpret breath analysis research
Serves as both an accessible primer for newcomers and a comprehensive reference for experienced researchers and professionals

Produktinformation

Utgivningsdatum2026-11-01
Mått191 x 235 x undefined mm
FormatHäftad
SpråkEngelska
Antal sidor756
Upplaga3
FörlagElsevier Science
ISBN9780443459870

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Analytisk kemi inom Naturvetenskap och teknik

Jonathan Beauchamp is manager of the Emissions Analytics and Diagnostics group at the Fraunhofer Institute for Process Engineering and Packaging IVV in Freising, Germany. He has been involved in academic and industrial breath research for the past 15 years and is currently principal investigator in several breath-related projects. He is an active member and current treasurer of the International Association of Breath Research (IABR). Cristina Davis is chair and professor of Mechanical and Aerospace Engineering at the University of California Davis, United States. Her research focuses on development of novel chemical and biological sensor systems and biomarker identification in agriculture and human/animal health monitoring. She has 12 issued patents and has coauthored over 100 peer-reviewed journal articles and book chapters. She is current chair-elect of IABR. Joachim Pleil is adjunct professor at the University of North Carolina, School of Public Health, United States. He has published over 150 journal articles, many involving breath biomarker research and statistical interpretation of breath-based data. He has retired from US Environmental Protection Agency after 32 years as a research scientist. He is currently a consultant for NASA on a pilot breathing assessment project and is a founding member of IABR.

PART A:Concepts in breath analysis1. Breath biomarkers and the exposome2. Breath sampling and standardization3. Physiological modelling of exhaled compoundsPART B: Breath constituents4. Endogenous volatiles and the breath volatilome5. Exhaled nitric oxide 6.Exhaled carbon monoxide7. Exhaled breath condensate and aerosolsPART C: Analytics8. Selected ion flow tube mass spectrometry9. Proton transfer reaction—mass spectrometry10. Ion mobility spectrometry11. Secondary electrospray ionization12. Sensor systems13. Optical spectroscopy14. Gas chromatography-mass spectrometry15. High-resolution mass spectrometryPART D: Breath tests16. 13C breath tests17. Breath monitoring in the intensive care unit18. Chronic obstructive pulmonary disease, smoking and vaping19. Clinical phenotyping 20.Breath analysis for respiratory infections21. Volatile biomarkers of viral infections22. Lifestyle applicationsPART E: Beyond human breath23. Biomarkers in urine and stool24. Volatile emissions from skin25. Mammalian bioreactors for volatile emissions26. Yeast and fungal volatilome27. Bacterial volatile emissionsPART F: Field applications28. Breath analysis in law enforcement29. Drugs in breath30. Urban search and rescue31. Breath analysis in constrained environments32. Breath analysis in occupational medicine33. Breath biomarkers in human xenobiotic exposure studies34. Canine olfactionPART G: Design and interpretation35. Clinical study design36. Challenges in clinical breath research development37. Mathematical interpretation of targeted volatilome data38. Preprocessing and analysis of volatilome data