Alternatives to Animal Testing

Hajime KojimaNational Institute of Health Sciences , Kawasaki, Kanagawa, JapanTroy SeidleHumane Society International , Montréal, QC, CanadaHorst SpielmannInstitut für Pharmazie Free University of Berlin, Berlin, Germany

• 1. Zebrafish, Danio rerio as a replacement alternative model useful in CKDu experiments.- 2. Testing Method Development and Validation for In Vitro Skin Irritation Testing (SIT) by Using Reconstructed Human Epidermis (RhE) Skin Equivalent - EPiTR.- 3. Development the technique for the Preparation and Characterization of Reconstructed Human Epidermis (RHE).- 4. Alternative Research (3Rs) in the World, Asia and Japan.- 5. Approaches to Reducing Animal Use for Acute Toxicity Testing: Retrospective Analyses of Pesticide Data.- 6. Progress in deleting the 1-year dog study for the safety assessment of pesticides.- 7. Cosmetic regulation and alternatives to animal experimentation in India.- 8. Guidance on the Use of Alternative Test Methods for the Safety Assessment of Cosmetics and Quasi-Drugs.- 9. Alternatives and Refinement for Animal Experimentation in Cancer Research.- 10. 3Rs in quality control of human vaccines: opportunities and barriers.- 11. The Use of Adverse Outcome Pathways (AOPs) to Support Chemical Safety Decisions within the Context of Integrated Approaches to Testing and Assessment (IATA).- 12. Mechanism-based evaluation system for hepato- and nephrotoxicity or carcinogenicity using omics technology.- 13. Alternative methods for developmental toxicity testing using mouse ESCs.- 14. Futuristic approach to alternative model organisms: Hydra stakes its claim.- 15. The Lush Prize and Young Researcher Asia Awards 2016.