Advancements of Mass Spectrometry in Biomedical Research

Dr. Costel C. Darie started his biomedical career as a nurse at the Murgeni Hospital, Romania. He received his BS and MS in biochemistry at the Alexandru Ioan Cuza University from Iasi, Romania, and performed research under Dr. Vlad Artenie. He continued his Ph.D. studies with Dr. Wolfgang Haehnel at the Albert-Ludwigs Universitaet, Freiburg, Germany, after which he worked in the labs of Drs. Paul M. Wassarman & Micsunica Platica (Mount Sinai School of Medicine) and Thomas A. Neubert (New York University Medical Center). He currently is a Full Professor of Chemistry and Biochemistry at Clarkson University, where he is the lead of the Biochemistry and Proteomics Laboratories. Dr. Alisa Woods received her BS in psychology from the State University of New York (SUNY) at Plattsburgh and her PhD in biology from the University of California, Irvine, with Dr. Christine Gall. She continued with post-doctoral training at the University of Freiburg, Germany, with Dr. Michael Frotscher and completed a Master's degree in Mental Health Counseling at the University of Massachusetts, Boston. She is currently a Research Associate Professor of Chemistry and  Biochemistry at Clarkson University, where she works in the Biochemistry and Proteomics Laboratories.

• Mass Spectrometry for Proteomics-Based Investigation.- MALDI Profiling and Applications in Medicine.- Proteome Imaging From Classic to Modern Mass Spectrometry Based Molecular Histology.- Mass Spectrometry Based Tissue Imaging of Small Molecules.- Sequencing Proteins from Bottom to Top Combining Techniques for Full Sequence Analysis of Glucokinase.- Proteomics and Non-proteomics Approaches to Study Stable and Transient Protein Protein Interactions.- Profiling Optimal Conditions for Capturing EDEM Proteins Complexes in Melanoma Using Mass Spectrometry.- The Methods Employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein Protein Interactions (PPIs).- Identification of Posttranslational Modifications (PTMs) of Proteins by Mass Spectrometry.- Sequence Variant and Posttranslational Modification Analysis During Cell Line Selection via High-Throughput Peptide Mapping.- Investigation of Antibody Drug Conjugates by Mass Spectrometry.- Mass Spectrometry and Computational Structural Biology-Based Investigation of Proteins and Peptides.- Strategies for Membrane Protein Analysis by Mass Spectrometry.- The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses.- Immuno Affinity Mass Spectrometry A Novel Approaches with Biomedical Relevance.- Developing Well-Annotated Species Specific Protein Databases Using Comparative Proteogenomics.- Role of Mass Spectrometry in Investigating a Novel Protein The Example of Tumor Differentiation Factor.etc.