Xenotransplantation

Basic Research and Clinical Applications

Inbunden, Engelska, 2002

Av Jeffrey L. Platt, Jeffrey Platt, Jeffrey L Platt

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Internationally recognized scientists, clinicians, and technologists review and explain the fundamental molecular and cellular biology that has been applied to the emerging field of transplant immunology and xenotransplantation, and what impact these advances might optimally have on medicine and science. The authoritative experts writing here-many of whom made the basic discoveries underlying the recent advances-examine the biological and immunological hurdles to xenotransplantation, illuminating how the immune system interacts with the xenograft and laying a practical foundation for the use of genetic engineering and animal transplants in the treatment of human disease.

Produktinformation

Utgivningsdatum2002-05-07
Mått155 x 235 x 24 mm
Vikt594 g
FormatInbunden
SpråkEngelska
Antal sidor270
FörlagHumana Press Inc.
ISBN9780896036741

Tillhör följande kategorier

Onkologi inom Medicin
Transplantationskirurgi inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Medicinsk etik och läkaretik inom Medicin

1 Molecular and Cellular Hurdles to Xenotransplantation.- 2 Pathological Responses to Xenotransplantation.- 3 Natural Xenoreactive Antibodies.- 4 Specificity of Xenoreactive Natural Antibodies.- 5 Biophysical Properties of Xenoreactive Natural Antibodies.- 6 The Origin of Xenoreactive Natural Antibodies.- 7 Synthesis of Carbohydrate Antigens Recognized by Xenoreactive Antibodies.- 8 The Complement Barrier to Xenotransplantation.- 9 Defects and Amplification of Costimulation Across the Species.- 10 Antibody-Dependent Effects on Cellular Immunity.- 11 Disordered Regulation of Coagulation and Platelet Activation in Xenotransplantation.- 12 Current Applications of Cellular Xenografts.

"This book provides a useful and concise review of the current status of xenotransplantion and introduces the reader to the remaining required developments before effective implementation of xenotransplantation can occur...The editor and authors are recognized authorities in the field of xenotransplantation and this book is an important addition to existing literature on this topic" - Doody's Health Sciences Book Review Journal