Wound Healing, Tissue Repair, and Regeneration in Diabetes

Debasis Bagchi earned his Ph.D. in Medicinal Chemistry in 1982 and is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy. He also serves as Chief Scientific Officer at Cepham Research Center and holds adjunct faculty appointments. Previously, he was Senior Vice President of Research & Development at InterHealth Nutraceuticals (1998–2011) and later Director of Innovation and Clinical Affairs at Iovate Health Sciences (2011–2013).Dr. Bagchi received the Master of the American College of Nutrition Award in 2010 and has held leadership roles including Past President of the American College of Nutrition and Past Chairman of the International Society of Nutraceuticals and Functional Foods. He contributes as an NIH peer reviewer and advisor to international health organizations.A prolific scholar, he has authored over 320 peer-reviewed papers, 30 books, and holds 18 patents. He also serves on editorial boards of numerous scientific journals.Amitava Das, PhD, is a Postdoctoral Researcher at Indiana Center for Regenerative Medicine and Engineering (ICRME), Indiana University School of Medicine. Dr. Das earned his Bachelor’s and Master’s in Pharmacy and Pharmaceutical Chemistry, respectively, from PES College of Pharmacy, Bangalore, India. He earned his PhD degree in Human Nutrition from The Ohio State University in 2016 after which he joined as a Postdoctoral Researcher in Department of Surgery at The Ohio State University Medical Center, and then moved to Indiana University in 2018. His research interests are tissue repair and regeneration in diabetes and Nutraceuticals. He has published over 20 research papers and numerous book chapters. Since 2017, Dr. Das is a member of the Editorial Board of Journal of American College of Nutrition and a Communications committee member of the Wound Healing Society. Dr. Das also serves as a reviewer for multiple prestigious journals. He has presented at various national and international conferences and is the recipient of several awards. Sashwati Roy, PhD is a Professor of Surgery and Director of Laser Capture Molecular Analysis facility at the Ohio State University Columbus Ohio. She received her PhD in 1994 in Physiology and Environmental Sciences. She completed her postdoctoral training from University of California, Berkeley. Her research interest include wound inflammation, mechanisms of resolution of diabetic wound inflammation, role of miRNA in tissue repair processes. Dr. Roy has over 150 peer review publications in high impact journals including Nature Nanotechnology, PNAS and Journal of Immunology. Dr. Roy is the President Elect of the Wound Healing Society. She serves in the Editorial Board of several Journals such as Physiological Genomics, Antioxidants and Redox Signaling. She is an expert in significance of macrophage and inflammation in chronic wounds. Dr. Roy’s research is funded by National Institute of Health (NIDDK, NIH).

• Part 1: Background and Overview1. Concept and stages of wound healing 2. Pathophysiology of Diabetic ulcers 3. Wound infection and inflammation4. The Angiogenic Response5. Fetal Wound Healing 6. The Extracellular matrix: its formation and role in wound healing7. Scarring and fibrosis8. Role of cytokines and chemokines in wound healing9. Dysregulated inflammation in diabetic wounds 10. Role of oxygen in diabetic wound healing11. Epigenetics of diabetic wound healing 12. Tissue regeneration13. Energetics and nutritional status of chronic and diabetic wounds14. Epidemiology of Diabetic wounds Part Two: Clinical Update and Therapeutic Standards15. Wound management and its principles16. Chronic wounds and its menaces17. Surgical Debridement and NPWT 18. Clinical management of DFU 19. Diabetic neuropathy20. Malignant woundsPart Three: Therapeutic Interventions21. Biomaterials used to treat diabetic wounds 22. Peptides to treat diabetic wounds23. Nutraceutical interventions of wound healing and inflammation24. Papaya: A natural remedy for diabetic wounds 25. Role of berries in wound healing Part Four: Future Directions26. MiRNA in diabetic wound healing27. Electroceuticals: an emerging field in wound healing28. Nano-electroporation and reprogramming