This book constitutes the proceedings of the 25th IFIP WG 5.4 International TRIZ Future Conference on AI-Powered Innovation and Inventive Design, TFC 2025, held in Paris, France, during November 5–7, 2025.The 48 full papers  included in this book were carefully reviewed and selected from 75 submissions. They were focused on topical section as below.Part I: Neuro-Symbolic and AI-Assisted Contradictions; Generative Agents for Ideation and Design; Tech Mining, Forecasting and Cross-Domain Exploration; Modeling, Verification and Optimization of Technical Systems and Frameworks for Digital Transformation and Industry 5.0. Part II Cognition, Causality and Systematic Prototyping; Innovation Governance and Standardization; Innovation Governance and Standardization; Data, Forecasting and Intelligent Services and User Experience and Interoperable Public Policies.