Women and Health

Dr. Rebecca Troisi is a research epidemiologist with expertise and extensive experience in the areas of reproductive health, cancer, and life course epidemiology at the Division of Cancer Epidemiology and Genetics, National Cancer Institute. Dr. Troisi leads the Diethylstilbestrol Follow-up Study and has many domestic and international collaborations including the Nordic Project. As well as having co-edited the second edition of Women and Health, she has authored over 150 peer-reviewed publications, many as first or last author, and several book chapters. Her current position at the National Institute of Health includes collaboration with the Office of Research on Women’s Health providing an overview and big picture regarding current issues and initiatives in this area. Dr. Kathryn Rexrode is the Chief of the Division of Women’s Health in the Department of Medicine at Brigham and Women’s Hospital (BWH) and an Associate Professor of Medicine at Harvard Medical School. Dr. Rexrode is a general internist and has broad and deep research experience in women’s health, with a particular expertise in cardiovascular disease in women. She leads multiple grants from the National institute of Health and is the author of more than 250 research publications. Dr. Rexrode is a Fellow of the American Heart Association and Chair of the Women and Special Populations Committee. Dr. Yvette Cozier is an Associate Professor of Epidemiology, and the Associate Dean of Diversity, Equity, Inclusion and Justice (DEIJ) at Boston University School of Public Health. She is also a Senior Epidemiologist at the Slone Epidemiology Center at Boston University School of Medicine. A social epidemiologist, Dr. Cozier’s overall research focus has been on the influence of psychosocial and structural factors on health - including racism and neighborhood socioeconomic status (SES). Dr. Cozier co-leads (MPI) the Black Women’s Health Study (BWHS), a prospective follow-up of over 59,000 African American women begun in 1995. She has published over 100 abstracts, manuscripts, invited commentaries and reviews, monographs, and book chapters on health disparities, cardiometabolic, and immune-mediated conditions including obesity, lupus, and sarcoidosis. Dr. Goldman’s career spans more than thirty-five years and includes extensive experience in research design, methodology, and analysis. As Director of Clinical Research, she supervised faculty and resident research in reproductive endocrinology and infertility, maternal-fetal medicine, urogynecology, and gynecologic oncology. Dr. Goldman completed graduate and post-graduate study in epidemiology at Harvard University’s School of Public Health where she also served on the faculty for more than a decade. During the development of the first edition of Women & Health she received a Health Sciences Fellowship at the Radcliffe Institute for Advanced Study at Harvard University. Dr. Goldman is a Fellow of the American College of Epidemiology and a lifetime member of the American Society for Reproductive Medicine. She was previously an Associate Editor of the American Journal of Epidemiology, a chartered member of the NIH IRAP study section, and an Investigator in the Cancer Epidemiology and Chemoprevention Research program at Dartmouth’s Norris Cotton Cancer Center.

• Section A Metalloenzymes1. Introduction to metalloenzymes: From bench to bedsideSection B Magnesium and calcium-containing enzymes2.1 DNA and RNA polymerases2.2 Reverse transcriptase2.3 Integrase2.4 Cyclin-dependent kinase 2 (CDK2)2.5 Catechol-O-methyltransferase (COMT)2.6 D-Alanine-D-alanine ligase2.7 Paraoxonases2.8 Phospholipases A2Section C Zinc enzymes3.1 Carbonic anhydrases3.2 Metallo-β-lactamases3.3 Bacterial zinc proteases3.4 Matrix metalloproteases3.5 A disintegrin and metalloproteinases (ADAMs) and tumor necrosis factor-alphaconverting enzyme (TACE)3.6 Angiotensin-converting enzyme3.7 Histidinol dehydrogenase3.8 Histone deacetylases and other epigenetic targets3.9 CD73 (5'-Ectonucleotidase)3.10 Glyoxalase II3.11 Glutamate carboxypeptidase II3.12 Neutral endopeptidase (neprilysin)Section D Other metalloenzymes4.1 The role of arginase in human health and disease4.2 Methionine aminopeptidases4.3 1-Deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme in the MEP terpenoid biosynthetic pathway— Its chemical mechanism and inhibitionSection E Nickel enzymes5.1 Urease5.2 Methyl-coenzyme M reductaseSection F Iron enzymes (heme-containing)6.1 Cyclooxygenase6.2 Cytochrome P450 (inhibitors for the metabolism of drugs)6.3 AromataseSection G Iron enzymes, non-heme containing7.1 Nonheme mono- and dioxygenases7.2 Indoleamine 2,3-dioxygenaseSection H Copper enzymes8.1 Superoxide dismutases inhibitors8.2 Tyrosinase enzyme and its inhibitors: An update of the literatureSection I Cadmium enzymes CAs9. CDCA1, a versatile member of the ξ-class of carbonic anhydrase familySection J Molybdenum enzymes10. Molybdenum enzymesSection K Tungsten-containing enzymes11. Tungsten-containing enzymes