Weedon's Skin Pathology

Dr Jim Patterson has been recognized as an outstanding teacher, practitioner, and mentor by many physician trainees in Dermatopathology, Dermatology, and Pathology. His knowledge and experience in clinical dermatology, combined with his outstanding skills in histopathology, have made him an internationally recognized authority who has contributed substantially to the field of dermatopathology. Areas of special interest include differential diagnosis in dermatopathology, inflammatory skin disease, panniculitis, malignant melanoma, cutaneous T- cell lymphoma and other cutaneous malignancies, opportunistic infections, and immunofluorescence studies.

• SECTION 1 Introduction1. What’s new in the sixth edition2. An approach to the interpretation of skin biopsies3. Diagnostic cluesSECTION 2 Tissue reaction patterns4. The lichenoid reaction pattern (“interface dermatitis”)5. The psoriasiform reaction pattern6. The spongiotic reaction pattern7. The vesiculobullous reaction pattern8. The granulomatous reaction pattern9. The vasculopathic reaction patternSECTION 3 The epidermis10. Disorders of epidermal maturation and keratinization11. Disorders of pigmentationSECTION 4 The dermis and subcutis12. Disorders of collagen13. Disorders of elastic tissue14. Cutaneous mucinoses15. Cutaneous deposits16. Diseases of cutaneous appendages17. Cysts, sinuses, and pits18. PanniculitisSECTION 5 The skin in systemic and miscellaneous diseases19. Metabolic and storage diseases20. Miscellaneous conditions21. Cutaneous drug reactions22. Reactions to physical agentsSECTION 6 Infections and infestations23. Cutaneous infections and infestations--histological patterns24. Bacterial and rickettsial infections25. Spirochetal infections26. Mycoses and algal infections27. Viral diseases28. Protozoal infections29. Marine injuries30. Helminth infestations31. Arthropod-induced diseasesSECTION 7 Tumors32. Tumors of the epidermis33. Lentigines, nevi, and melanomas34. Tumors of cutaneous appendages35. Tumors and tumor-like proliferations of fibrous and related tissues36. Tumors of fat37. Tumors of muscle, cartilage, and bone38. Neural and neuroendocrine tumors39. Vascular tumors40. Cutaneous metastases41. Cutaneous infiltrates--nonlymphoid42. Cutaneous infiltrates--lymphomatous and leukemic

"This new edition continues this trend with comprehensive, detailed yet concise coverage of the essential dermatopathology entities that trainees and practicing pathologists might encounter daily, as well as rarer ones.... [also] continues to provide excellent descriptions of the key features, which can help readers hone in on a diagnosis despite this heterogeneity.... [it] has been essential in helping me traverse this complex landscape to get to the right diagnosis and report for the patient. In particular, the choice of images within the text is excellent in highlighting the key features accurately, which is laudable again, given this heterogeneity.... This is no easy task but I think the new edition does an admirable job. I highly recommend this text to all trainees but especially those interested in dermatopathology." Review by Dr Ryan Clark, Trainee Section Editor, The Bulletin (Royal College of Pathologists), October 2025"...a comprehensive and extensively illustrated reference that provides current and authoritative information on dermatopathology.... [Also] provides detailed and comprehensive knowledge on all aspects of skin pathology including disease etiology, pathogenesis, clinical presentation, histopathology, and differential diagnosis. This edition is an essential resource for dermatopathologists, general pathologists, and trainees due to its breadth of both clinical and histopathological content, making it an invaluable asset for everyone handling skin biopsies and excisions.... There are about 2,000 high-quality histologic images and illustrated schemes with instructive figure legends throughout the book,... the index at the end of is thorough and easy to use.... It is ideal for daily use as a reference but also an excellent training resource. Key highlights of this book are the detailed descriptions and over 1,800 microphotographic illustrations that highlight various histologic features to diagnose each disease entity correctly." ©Doody's Book Review Service, 2025, Katharina Wiedemeyer, MD (University of Michigan Medical School) Doody's Score: 99, 5 stars!