Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis

Pathogenesis, Treatment and Disease Control

Inbunden, Engelska, 2025

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This reference book explores various aspects of visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL), including their pathophysiology, treatment options, and disease control strategies. The initial chapter provides an overview of VL, its global impact, and pathogenesis. It also examines the development of PKDL from VL, outlining the transition from the acute form of the disease to the chronic dermal condition. The book further explores the symptoms and diagnosis of both VL and PKDL. Furthermore, the book delves into the immunopathogenesis of both VL and PKDL, shedding light on the complex interactions between the parasite and the host immune system. It reviews the impact of environmental factors, particularly the contamination of arsenic and antimony in drinking water, on the progression of the disease. Lastly, the book discusses preventive measures for PKDL and highlights the major challenges in effectively implementing these strategies. This book serves as a useful resource for researchers, healthcare professionals, and policymakers seeking to deepen their understanding of these diseases and develop effective strategies for their prevention and control.Key featuresProvides in-depth coverage of VL and PKDL, including pathogenesis, treatment, and disease control strategiesElucidates the symptoms and diagnostic methods for VL and PKDLOffers insights into the complex immunopathogenesis of VL and PKDL, exploring the interactions between parasites and host immune systemExamines treatment options for both VL and PKDL, including current therapeutic approaches and emerging strategiesReviews the impact of environmental factors, such as arsenic and antimony contamination, on the disease progressionDiscusses preventive measures and challenges in implementing effective strategies for PKDL prevention and control

Produktinformation

Utgivningsdatum2025-04-02
Mått178 x 254 x 18 mm
Vikt600 g
FormatInbunden
SpråkEngelska
Antal sidor224
FörlagTaylor & Francis Ltd
ISBN9781032633053

Tillhör följande kategorier

Onkologi inom Medicin
Epidemiologi och medicinsk statistik inom Medicin
Biologi inom Naturvetenskap och teknik
Infektionssjukdomar och smittsamma sjukdomar inom Medicin

Dr. Veer Singh is currently working as Young Scientist (DHR) at the Department of Biochemistry, Rajendra Memorial Research Institute of Medical Sciences, Patna, India. He got PhD from the Indian Institute of Technology (Banaras Hindu University), Varanasi. He has more than 40 publications and his area of work involved Environmental contamination & toxicity, the role of drinking water heavy metals contamination in visceral leishmaniasis (VL) & post-kala-azar dermal leishmaniasis (PKDL) development.Dr. Ashish Kumar is currently working as Scientist-C and Head of Department at the Department of Biochemistry, Rajendra Memorial Research Institute of Medical Sciences, and Patna, India. He has published more than 40 publications in International/national journals. He has received several awards and received several funding (sponsored projects) from many national and international agencies. Currently, 4 doctoral and 2 postdoctoral students are working under the supervision of Dr. Ashish Kumar. Dr. Kumar is working in the interdisciplinary area of life science. His work is mainly focused on visceral leishmaniasis (VL) and post kala-azar dermal leishmaniasis (PKDL). He is also working on VL and PKDL diagnosis, treatment and environmental impacts on disease development.

Preface. Acknowledgements. Editors. Contributors. Chapter 1 General Introduction to Visceral Leishmaniasis. Chapter 2 Geographical Distribution of VL and PKDL in India. Chapter 3 Visceral Leishmaniasis as a Public Health Problem in India: Action Toward its Elimination. Chapter 4 Pathogenesis of Visceral Leishmaniasis. Chapter 5 A Current Scenario of Drug Discovery Against Visceral Leishmaniasis. Chapter 6 Major Challenges in Visceral Leishmaniasis Treatment. Chapter 7 Post-kala-azar Dermal Leishmaniasis Development from Visceral Leishmaniasis. Chapter 8 Symptoms and Diagnosis of Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis. Chapter 9 Molecular Mechanism of PKDL Development. Chapter 10 Immunopathogenesis of Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis. Chapter 11 A Recent Update on Visceral Leishmaniasis and Post-kala-azar Dermal Leishmaniasis: Epidemiology, Diagnosis, and Treatments. Chapter 12 Review of Existing Control Measures for VL and PKDL: Innovative Approaches to Vector Control, Case Management, Vaccine Development, and Community Education. Chapter 13 Public Health Implications and Challenges of VL and PKDL. Chapter 14 Role of Environmental Factors on the Development of PKDL. Chapter 15 Arsenic and Antimony Toxicity in Drinking Water and Their Roles in the Development of PKDL. Chapter 16 Government Policies toward Providing Safe Drinking Water to the Public. Chapter 17 Factors Influencing the Development of Post-kala-azar Dermal Leishmaniasis. Index.