The Venom symbiote claims a new host, who just happens to be one of Spider-Man’s greatest enemies!

Venom’s murderous offspring, Carnage, is about to reproduce himself — and Venom won’t stand for it! Only a now Eddie Brock-less Venom can save the life of its symbiotic grand-child. But is the new arrival named Toxin destined to be an even greater monster than those that came before it — or something else entirely? Then Venom forms a new bond — but is Angelo Fortunato, son of a mob boss, man enough to host a symbiote? Maybe Mac Gargan, A.K.A. the sinister Scorpion, is more Venom’s speed — but then can Spider-Man triumph against two of his most bitter foes combined?! In a world where Norman Osborn is in charge, Spidey villains enjoy fresh opportunities — and for the new Venom, that means a place on Osborn’s Thunderbolts! But is he ready to play hero? Plus: Look back at the dark origin of Eddie Brock that led him to join with Venom!

COLLECTING: Venom vs. Carnage (2004) #1-4; Marvel Knights Spider-Man (2004) #7-8, 11; Sensational Spider-Man (2006) #38-39; Thunderbolts: Reason in Madness (2008) One-Shot; Venom: Dark Origin (2008) #1-5; material from Civil War: Choosing Sides (2006), Spider-Man Family (2007) #3

Written by Peter Milligan, Mark Millar, Robert Aguirre-Sacasa, Christos Gage, Zeb Wells & More
Penciled by Clayton Crain, Terry Dodson, Frank Cho, Lee Weeks, Ben Oliver, Angel Medina & More