Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment

Advancing an Integrated Approach

Inbunden, Engelska, 2020

AvDavid J. Libon,Melissa Lamar,Rodney A. Swenson,Kenneth M. Heilman,Rowan University) Libon, David J. (Professor of Geriatrics, Gerontology, and Psychology, Professor of Geriatrics, Gerontology, and Psychology,Rush Alzheimer's Disease Center) Lamar, Melissa (Associate Professor, Associate Professor,University of North Dakota School of Medicine and Health Sciences) Swenson, Rodney A. (Clinical Professor of Psychiatry and Behavioral Science, Clinical Professor of Psychiatry and Behavioral Science,University of Florida) Heilman, Kenneth M. (Distinguished Professor Emeritus, Distinguished Professor Emeritus, Department of Neurology,Libon

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Alzheimer's disease (AD) and vascular dementia (VaD) are commonly viewed as the first and second most common types of dementia, respectively. The traditional paradigm has been to view and treat each illness as a separate entity with a separate pathophysiology. However, clinical and pathological studies suggest that the boundary separating AD and VaD, as well as their mild cognitive impairment (MCI) analogs, is not well defined. Thus, there is increased interest in viewing these diseases along a spectrum because of the significant overlap in the characterization and diagnosis of AD, VaD, and MCI. The focus of this edited volume is to examine how AD and VaD, as well as their MCI analogs, are best viewed as a heterogeneous, intersecting, if not a continuous disease state rather than separate, distinct entities. This book examines this approach by providing empirically based evidence, reviews of the literature, and chapters by key leaders in the field and will be of interest to clinical neuropsychologists and anyone studying or treating dementia in its many forms.

Produktinformation

Utgivningsdatum2020-04-22
Mått160 x 239 x 35 mm
Vikt839 g
FormatInbunden
SpråkEngelska
Antal sidor504
FörlagOUP USA
ISBN9780190634230

Tillhör följande kategorier

Geriatrik inom Medicin
Neurologi och klinisk neurofysiologi inom Medicin
Biologisk psykologi och neuropsykologi inom Psykologi och pedagogik
Kognitiv psykologi inom Psykologi och pedagogik
Medicin: allmänt inom Medicin
Alzheimer, demens inom Medicin

David J. Libon is Professor of Geriatrics, Gerontology, and Psychology at the New Jersey Institute for Successful Aging, School of Osteopathic Medicine, Rowan University. Melissa Lamar is a licensed Clinical Neuropsychologist and an Associate Professor in the Department of Behavioral Sciences and a full-time Cognitive Neuroscientist within the Rush Alzheimer's Disease Center at the Rush University Medical Center.Rodney A. Swenson is a board certified Neuropsychologist and Clinical Professor of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences.Kenneth M. Heilman is a Distinguished Professor Emeritus at the University of Florida.

PrefacePart 1: Epidemiology and Neuropsychology Chapter 1: Vascular risk factors and their relationship to brain aging: Findings from the Framingham Heart StudyChapter 2: Neuropsychological Profiles in Alzheimer's/ Vascular Spectrum DementiaChapter 3: Neuropsychological Diagnostic Criteria for Mild Cognitive Impairment due to Alzheimer's DiseaseChapter 4: Vascular Cognitive ImpairmentChapter 5: Decline in Everyday Functioning in MCI and Dementia: A Neuropsychological PerspectiveChapter 6: Heterogeneity in Dementia and MCI: Using Statistical Modeling TechniquesChapter 7: Apraxic and Action-Intentional Disorders Associated With Vascular And Degenerative Dementing DiseasesPart 2: NeuroimagingChapter 8: Cerebral small vessel disease and the risk of dementia and cognition declineChapter 9: Structural MRI in Alzheimer's disease: Are we measuring the right stuffChapter 10: Advances in Multi-Modal Imaging Across the Spectrum of Normal to Pathological aging: Incorporating Vascular Comorbidities Common to Alzheimer's disease and Vascular DementiaPart 3: Blood-Brain-Barrier and Cardiogenic MechanismsChapter 11: The Blood-Brain Barrier in Cognitive Decline and Alzheimer's DiseaseChapter 12: Arterial Stiffening and Cerebrovascular Resistance in Cognitive Decline and Alzheimer's DiseaseChapter 13: Hemodynamics in Alzheimer's Disease and Vascular Cognitive Impairment & Dementia Part 4: Neuropathological and Neurophysiological MechanismsChapter 14: Neuropathology of AD/ VaD Dementia Chapter 15: Potential of blood- and CSF-based biomarkers for AD diagnosticsChapter 16: Unravelling the Role of Mitochondria in Alzheimer's disease: Toward Assembling the PuzzlePart 5: Treatment and InterventionChapter 17: Dementia and Elective Surgeries: Considerations for NeuropsychologistsChapter 18: Management of Mild Cognitive Impairment