Vaccine Design

Vaccines have long been used to combat infectious disease, however the last decade has witnessed a revolution in the approach to vaccine design and development. No longer is there a need to rely on the laborious classical methods such as attenuation or killing the pathogen. Now sophisticated technologies such as genomics, proteomics, functional genomics, and synthetic chemistry can be used for the rational identification of antigens, the synthesis of complex glycans, the generation of engineered carrier proteins, and much more. Never has research in this area been more exciting. In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies. The book has been divided into two parts. The first part reviews the technologies and approaches used to identify, generate and test new vaccines. Topics include: new strategies to identify protective antigens, generati