Understanding DNA Ancestry

Sheldon Krimsky is Lenore Stern Professor of Humanities and Social Sciences and Adjunct Professor of Public Health and Community Medicine at Tufts University, Massachusetts, USA. His research has focused on the linkages between science/technology, ethics/values and public policy. His areas of specialization include biomedical sciences, bioethics, science and technology studies, risk assessment and communication, social history of science, and environmental health. He is the author of over 200 articles and reviews, and author, co-author or editor of 16 books.

• 1. Introduction; 2. The business of DNA ancestry; 3. Geographical origins and movements of early human populations; 4. The science behind DNA ancestry testing; 5. Ancestry informative markers; 6. Ancestry DNA population reference panels; 7. Comparing a donor's DNA to reference panel populations; 8. Probing your DNA; 9. Forensic applications of ancestry DNA results; 10. Privacy, personal identity and legal issues; 11. Discovering unknown, missing or mistaken relatives; 12. Accuracy, consistency and validation of DNA ancestry tests; 13. Conclusion.

'Sheldon's book represents a much needed historical, technical, and ethical treatment of this rapidly evolving and growing industry. It tackles a complex topic that many are fascinated by but few have the educational background to appreciate un-shepherded fully, and does so in a way that is accessible and easy to internalize by the very lay readers who have literally built the entire industry with their demand. His book is not only timely, but way, way overdue … this book is in my view instrumental for anyone considering a genetic ancestry test. If you are a lay consumer of genetic ancestry testing products, it has my highest recommendation for you.' Tony N. Frudakis, Ph.D., Forensic Scientist, Albuquerque Police Department DNA Laboratory, and Founder DNAPrint Genomics, Inc. (1999)