Edward J. Khantzian, MD, is clinical professor of psychiatry at Harvard Medical School and associate chief of psychiatry at Tewksbury Hospital, Tewksbury, MA. Mark J. Albanese, MD, is director of Addictions Treatment Services at Cambridge Health Alliance and assistant clinical professor of psychiatry at Harvard Medical School.

• Chapter 1 Foreword Chapter 2 Why Self Medication? Chapter 3 Addiction: Disease or Disorder Chapter 4 The Self-Medication Hypothesis and Addiction as a Problem in Self-Regulation Chapter 5 Self-Medication Hypothesis Research Chapter 6 Contexts and Models for Understanding Addiction—A Brief Overview Chapter 7 Suffering and Self-Medication Chapter 8 Self-Medication, Psychiatric Disorders, and Emotional Pain Chapter 9 Trauma and the Self-Medication Hypothesis Chapter 10 Addiction and the Perpetuation of Suffering Chapter 11 Nicotine, Marijuana and the Self-Medication Hypothesis Chapter 12 Gambling and Other Behavioral Disorders Chapter 13 The Neurobiology of Addictions Chapter 14 How the Self-Medication Hypothesis Can Guide Treatment and Recovery Chapter 15 Conclusion Chapter 16 Afterword

Doctors Khantzian and Albanese wrote this book directly from their experience with patients, as well as their close involvement with vast research. This blessedly brief and un-confusing volume, a tour de force that is original, useful, and wise. These two doctors, who have given their professional lives to understanding and helping those who are affected by addictions, now give to the world a consummate gift: what they know. Combining knowledge with love, the authors have moved the dialogue on addictions to an entirely new level. -- Edward Hallowell, MD, author of Driven to Distraction and many other books; Founder of The Hallowell Centers; host of the weekly podcast Distraction Understanding Addiction as Self Medication provides a clear explanation of the reasons behind many addictions, emphasizing the pain experienced by many addicted people. This is an important and readable book that provides useful insights to professionals, families, and friends, as well as individuals suffering with addictions. -- Kathleen T. Brady, MD, PhD, General Clinical Research Center Recommended. -- W. Feigelman CHOICE, April 2009 Understanding Addiction as Self-Medication is a worthwhile addition to the reading lists of counselors at all levels of experience...Understanding Addiction as Self-Medication pulls together a credible, non-judgmental theory of addiction. Professional Counselor, April 2009 This book clearly explains the self-medication hypothesis, updates and modernizes it, and provides very useful insights and tools for clinicians, patients, and their families...What makes this a special book is the skill, understanding, and attitudes of these very gifted, experienced, and creative therapists... The writing is clear, enjoyable and a fast read. Moreover, the book is written at a level that can be easily comprehended by sophisticated patients, their families, and workers in allied fields. -- Richard Frances, MD, Clinical Professor of Psychiatry, New York University This book is an admirably clear exposition of how a universal human need to manage distress and control emotions can take extreme forms in addicted individuals, leading to perilous solutions and chemical careers. Doctors Khantzian and Albanese creatively use the Self Medication Hypothesis to explain multiple pathways into addiction and describe various exist routes, signifying hope, help and resolution. -- Martin Weegman, consultant clinical psychologist and group analyst, Gatehouse Drug Service Understanding Addiction is an easy and often engaging read and will primarily be useful for patients, families, and perhaps addiction therapists ... [The authors] emphasize both the importance of other contributions to addictive disorders, such as genetic, social, and family influences, and the need to utilize a wide range of treatment approaches, including agonist therapies and other medications ... Perhaps the most important contribution of Understanding Addiction is to remind us of the distinct experience, personal history, and intense suffering of the addicted patient. Am J Pyschiatry, November 2009