Koichi Terasaka is a professor at the Department of Applied Chemistry, Keio University, Japan. He is also chair of the Union of Fine Bubble Scientists and Engineers, director of the Fine Bubble Industries Association, and expert of the ISO/TC 281 (fine bubble technology) committee. He is a chemical engineer who has been involved with bubble engineering since the 1980s and has recently been working on industrial application of UFBs.Kyuichi Yasui is a senior research scientist at the National Institute of Advanced Industrial Science and Technology (AIST), Japan. He received his PhD from the Department of Physics, Waseda University, Japan, in 1996. His current research focuses on numerical simulations on UFBs and other topics in sonochemistry, sonoluminescence, acoustic cavitation, and nanocrystalsWataru Kanematsu is a former principal research manager at AIST. He is involved in research on characterization of UFBs and UFB-containing liquid. Industrial standardization of characterization technology is another technical interest for him.Nobuhiro Aya is a supervisory innovation coordinator at AIST. His scientific interests are focused mainly on fine bubbles and fine particles and also on methodological issues on combination and integration of various technologies and improvement of industrial/social usage of technologies. He is also the committee manager of the ISO/TC 281 (fine bubble technology) since its establishment in 2013.

• 1. History of Ultrafine Bubbles 2. Introduction to Experiments 3. Micro- and Ultrafine Bubbles Observed by Transmission Electron Microscopy Using Quick-Freeze Replica Technique 4. Real UFB Sample Measurements: A Few Cases 5. Theory of Ultrafine Bubbles 6. Study of Ultrafine Bubble Stabilization by Organic Material Adhesion 7. Cleaning with Ultrafine Bubble Water 8. Biological Effects and Applications of Ultrafine Bubbles 9. Recent Trends in Application of Encapsulated Ultrafine Bubbles in Medicine 10. Dental Application of Ozone Ultrafine Bubble Water 11. Preservability of Ultrafine Bubbles

“This is the first outstanding book focusing on the comprehensive features of ultrafine bubbles (UFBs). It covers their versatile aspects such as history, fundamentals, and latest applications, and in particular, their existence, stability, and radical formations. It is strongly recommended not only for researchers but also beginners interested in UFBs and wishing to gain new knowledge on the emerging UFB science and technology.”Prof. Emer. Kiyoshi YoshikawaKyoto University, Japan“This book is the bible of UFB research, discussing the characteristics, generation methods, and industrial applications of UFBs, as well as mechanisms of their various effects.”Prof. Takashi HataNational Institute of Technology, Kochi College, Japan

Koichi Terasaka is a professor at the Department of Applied Chemistry, Keio University, Japan. He is also chair of the Union of Fine Bubble Scientists and Engineers, director of the Fine Bubble Industries Association, and expert of the ISO/TC 281 (fine bubble technology) committee. He is a chemical engineer who has been involved with bubble engineering since the 1980s and has recently been working on industrial application of UFBs.Kyuichi Yasui is a senior research scientist at the National Institute of Advanced Industrial Science and Technology (AIST), Japan. He received his PhD from the Department of Physics, Waseda University, Japan, in 1996. His current research focuses on numerical simulations on UFBs and other topics in sonochemistry, sonoluminescence, acoustic cavitation, and nanocrystalsWataru Kanematsu is a former principal research manager at AIST. He is involved in research on characterization of UFBs and UFB-containing liquid. Industrial standardization of characterization technology is another technical interest for him.Nobuhiro Aya is a supervisory innovation coordinator at AIST. His scientific interests are focused mainly on fine bubbles and fine particles and also on methodological issues on combination and integration of various technologies and improvement of industrial/social usage of technologies. He is also the committee manager of the ISO/TC 281 (fine bubble technology) since its establishment in 2013.

• 1. History of Ultrafine Bubbles 2. Introduction to Experiments 3. Micro- and Ultrafine Bubbles Observed by Transmission Electron Microscopy Using Quick-Freeze Replica Technique 4. Real UFB Sample Measurements: A Few Cases 5. Theory of Ultrafine Bubbles 6. Study of Ultrafine Bubble Stabilization by Organic Material Adhesion 7. Cleaning with Ultrafine Bubble Water 8. Biological Effects and Applications of Ultrafine Bubbles 9. Recent Trends in Application of Encapsulated Ultrafine Bubbles in Medicine 10. Dental Application of Ozone Ultrafine Bubble Water 11. Preservability of Ultrafine Bubbles

“This is the first outstanding book focusing on the comprehensive features of ultrafine bubbles (UFBs). It covers their versatile aspects such as history, fundamentals, and latest applications, and in particular, their existence, stability, and radical formations. It is strongly recommended not only for researchers but also beginners interested in UFBs and wishing to gain new knowledge on the emerging UFB science and technology.”Prof. Emer. Kiyoshi YoshikawaKyoto University, Japan“This book is the bible of UFB research, discussing the characteristics, generation methods, and industrial applications of UFBs, as well as mechanisms of their various effects.”Prof. Takashi HataNational Institute of Technology, Kochi College, Japan

Koichi Terasaka is a professor at the Department of Applied Chemistry, Keio University, Japan. He is also chair of the Union of Fine Bubble Scientists and Engineers, director of the Fine Bubble Industries Association, and expert of the ISO/TC 281 (fine bubble technology) committee. He is a chemical engineer who has been involved with bubble engineering since the 1980s and has recently been working on industrial application of UFBs.Kyuichi Yasui is a senior research scientist at the National Institute of Advanced Industrial Science and Technology (AIST), Japan. He received his PhD from the Department of Physics, Waseda University, Japan, in 1996. His current research focuses on numerical simulations on UFBs and other topics in sonochemistry, sonoluminescence, acoustic cavitation, and nanocrystalsWataru Kanematsu is a former principal research manager at AIST. He is involved in research on characterization of UFBs and UFB-containing liquid. Industrial standardization of characterization technology is another technical interest for him.Nobuhiro Aya is a supervisory innovation coordinator at AIST. His scientific interests are focused mainly on fine bubbles and fine particles and also on methodological issues on combination and integration of various technologies and improvement of industrial/social usage of technologies. He is also the committee manager of the ISO/TC 281 (fine bubble technology) since its establishment in 2013.

• 1. History of Ultrafine Bubbles 2. Introduction to Experiments 3. Micro- and Ultrafine Bubbles Observed by Transmission Electron Microscopy Using Quick-Freeze Replica Technique 4. Real UFB Sample Measurements: A Few Cases 5. Theory of Ultrafine Bubbles 6. Study of Ultrafine Bubble Stabilization by Organic Material Adhesion 7. Cleaning with Ultrafine Bubble Water 8. Biological Effects and Applications of Ultrafine Bubbles 9. Recent Trends in Application of Encapsulated Ultrafine Bubbles in Medicine 10. Dental Application of Ozone Ultrafine Bubble Water 11. Preservability of Ultrafine Bubbles

“This is the first outstanding book focusing on the comprehensive features of ultrafine bubbles (UFBs). It covers their versatile aspects such as history, fundamentals, and latest applications, and in particular, their existence, stability, and radical formations. It is strongly recommended not only for researchers but also beginners interested in UFBs and wishing to gain new knowledge on the emerging UFB science and technology.”Prof. Emer. Kiyoshi YoshikawaKyoto University, Japan“This book is the bible of UFB research, discussing the characteristics, generation methods, and industrial applications of UFBs, as well as mechanisms of their various effects.”Prof. Takashi HataNational Institute of Technology, Kochi College, Japan