Barbara Simon, MDDivision Chief and Assistant Professor, Division of Endocrinology, Drexel University College of Medicine, Philadelphia, Serge Jabbour, MDAssociate Professor of Medicine, Division of Endocrinology, Diabetes, and Metabolic Diseases, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PAJeremy Flood, MD Assistant Professor, Division of Endocrinology, Drexel University College of Medicine, Philadephia, PA

• OUTLINE:1. Introduction - Epidemiology - At-risk populations - Health and socio-economic impact 2. Classification and Pathophysiology- Definition, classification and diagnosis- Pathogenesis, including polyglandular autoimmunity- Predication and prevention- LADA (Latent Autoimmune Diabetes of the Adult)- Recognition/ Features in adults with new onset type 1 /LADA 3. Management- Blood glucose monitoring: glycated hemoglobin, fructosamine, meters and sensors- Diabetes education, nutrition, exercise and special situations (holiday, travel)- Insulin therapy (sample insulin regimens)- Continuous Subcutaneous Insulin Infusion CSII (insulin pumps)- Pramlintide- Other therapies, including metformin and thiazolidinediones 4. Complications- Hyperglycemia and tissue damage including data from DCCT/EDIC- Retinopathy- Nephropathy- Neuropathy- Macrovascular disease- Hypoglycemia 5. Special Settings/Situations- Pregnancy- Inpatient management- Psychology, including depression and eating disorders- Pancreas and islet transplantation- Future therapies and devices 6. Provider and patient resources - Patient assessment tools - Monitoring and follow-up tools 7. References

"I agree that a reference text/manual that targets PCPs in the area of type 1 diabetes evaluation and management would be of benefit." -- Luigi Meneghini, MD, MBA, Associate Professor of Clinical Medicine; Director, Eleanor and Joseph Koscow Diabetes Center; Associate Director for Clinical Affiars, Diabetes Research Institute, University of Miami School of Medicine, Miami, FL"Yes [there is a need for such a text], concise pocket references that are easy to use and find information quickly are always nice to have - one reference book is easier to use than multiple for type 1 diabetes management. . .The draft outline is appropriate." -- Aaron Michels, MD, Endocrine Fellow, the University of Colorado, Denver, Denver, Colorado"I think when you list the other texts out there that are so bulky and big - I can certainly see a need for such a text. . . . Yes, would support such a publication." -- Tina K. Thethi, MD, MPH, Assistant Professor of Medicine, Section of Endocrinology, School of Medicine, Tulane University, New Orleans, LA