Since the publication of the previous edition of the Tumors of the Central Nervous System there have been impactful discoveries, evolving diagnostic classifications, and rapid technical advances that have significantly reshaped the field. In the spirit of the original series, this atlas keeps diagnostic pathology at the core of the discussion, reinforced by a wide array of illustrative material to support the practicing diagnostic pathologist who encounters these tumors and pseudoneoplastic conditions in daily practice to make a meaningful contribution to the care of patients we are privileged to serve.