Translational Cardiology

Cam Patterson, MD, MBAMcAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USAMonte S. Willis, MD, PhDMcAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USA

• Relationship Between Myocardial Ischemia/Reperfusion and Time-of-Day.- Phosphotransfer Reactions in the Failing Heart.- Mitochondria in Cardiac Disease.- PPAR/PGC-1 Regulation of Metabolism in Cardiac Disease.- AMPK and Metabolic Remodeling in Cardiac Disease.- Mechanotransduction in Cardiac Hypertrophy and Ischemia.- Cardiac Plasticity in Health and Disease.- Ubiquitylation‐Dependent Signaling in Heart Disease.- Mechanisms of Cardiac Dysfunction Associated with Cancer Therapeutics.- Molecular Basis of Cardiac Development and Congenital Heart Disease.- Cellular Therapy for the Infarcted Myocardium.- Novel Approaches to Deliver Molecular Therapeutics in Cardiac Disease Using Adeno-Associated Virus Vectors.- Novel Delivery of Molecular Therapeutics to the Heart Using Non-Biologic Constructs (PPMO/Morpholino) in Muscular Dystrophy.- Molecular Imaging of Cardiovascular Disease.

From the reviews: "This is an introduction to evolving concepts in biochemical and cellular signaling pathways in cardiac myocyte metabolism. ... The target audience includes students, physicians in training, advanced practice clinicians, and practicing physicians from a variety of specialties involved in treating patients with cardiac disease. ... The topics this book covers are evolving and include a broad array of information that introduces many cutting edge concepts. It is a valuable resource that will pave the way for innovative therapeutic methods for cardiac diseases." (Nay Htyte, Doody's Review Service, October, 2012)