Translational Autoimmunity, Volume 5

Challenges for Autoimmune Diseases

Häftad, Engelska, 2022

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Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing.

Describes challenges in the diagnosis, management and treatment of autoimmune diseases
Highlights major difficulties in the diagnosis and management of autoimmune diseases
Reflects important remediable deficiencies in current management
Meets the needs of basic scientists, clinicians and translational scientists and industry partners

Produktinformation

Utgivningsdatum2022-09-14
Mått191 x 235 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
SerieTranslational Immunology
Antal sidor418
FörlagElsevier Science
ISBN9780323853897

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Onkologi inom Medicin

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of the Universal Scientific Education and Research Network (USERN). Professor Rezaei has already been the Director of more than 55 research projects and has designed and participated in several international collaborative projects. Professor Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 35 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.

1. Introduction on Challenges for Autoimmune Diseases 2. From horror autotoxicus to autoimmunity3. Flow cytometry in the diagnosis of autoimmune related lymphoproliferative disorder4. Autoantigens in atopic dermatitis: the characterization of autoantigens and their diagnostic value5. Current paradigms and challenges in vitiligo translational research6. The role of the kynurenine-pathway aryl hydrocarbon receptor axis in autoimmune diseases of the skin7. COVID-19 in Childhood and Phenotypes of Pediatric Inflammatory Multisystem Syndrome8. Challenges for epigenetics of periodontitis9. Neutrophil extracellular traps in autoimmunity, renal diseases, and transplantation10. Membranous nephropathy and the role of autoantibodies in its diagnosis and evolution11. Testicular immune tolerance and viral infections12. Ophthalmologic manifestations and management of systemic autoimmune diseases13. Challenges for diagnosis and treatment of primary biliary cholangitis14. Modelling autoimmune cholangiopathies as infectious disease15. Bullous skin diseases and epitope-spreading16. Dermatologic autoimmunity associated with immune checkpoints inhibitors17. Insights and strategies to promote immune tolerance in allogenic hematopoietic stem cell transplantation recipients18. The potential of cellular transplantation to harness autoimmunity and reverse clinical diabetes