Edited by Jakob Edler, Managing Director, Fraunhofer Institute for Systems and Innovation Research ISI, Germany and Professor of Innovation Policy and Strategy, University of Manchester, UK, Mireille Matt, Senior Research Scientist, French National Institute for Research on Agriculture, Food and Environment (INRAE), France, Wolfgang Polt, Formerly Director of POLICIES, Joanneum Research, Austria and Matthias Weber, Head, Center for Innovation Systems and Policy, AIT (Austrian Institute of Technology), Austria and Professor of Innovation Policy, Université Gustave Eiffel, France

• ContentsIntroduction: the motivation for this volume and an overview of its contributions 1Jakob Edler, Mireille Matt, Wolfgang Polt and Matthias WeberPART I TRANSFORMATIVE MISSION-ORIENTED STI POLICY: THEORYAND CONCEPT1 Transformative mission-oriented STI policy: theoretical and conceptualrationales, intervention logics and challenges of an emerging type of STIpolicies 16Jakob Edler, Mireille Matt, Wolfgang Polt and Matthias Weber2 From formulation to implementation: conceptualizing mission-orientedpolicies as multi-stage translation processes 36Florian Wittmann, Miriam Hufnagl, Florian Roth, Merve Yorulmaz,Ralf Lindner and Stephanie Daimer3 Missions as a boundary object in umbrella frameworks: the case of theDutch mission-oriented top sector and innovation policy 53Matthijs Janssen, Joeri Wesseling, Jonas Torrens, Matthias Weber andCaetano C. R. PennaPART II TRANSFORMATIVE MISSION-ORIENTED STI POLICIES INDIFFERENT POLITICAL SYSTEMS AND ON DIFFERENT LEVELS4 Mission-oriented innovation policies in Europe: from the normative to theepistemic turn? 78Rainer Kattel and Mariana Mazzucato5 The formative evaluation of open-ended transformative missions: theVinnova experience in the food system 97Caetano C. R. Penna, Johan Schot, Diana Velasco and Jordi Molas-Gallart6 Challenges and opportunities of mission-oriented innovation policies forrealising transformative agendas: general principles and application to thecase of the fight against climate change 118Philippe Larrue7 Transformative missions as part of sustainability research programmes:experiences from the German FONA framework programme 144Rainer Walz, Susanne Bührer and Sarah Seus8 Conversion of the green mission for transformation-oriented industrialinnovation: green growth and 2050 carbon neutrality in South Korea 171Soohong Eum9 Mission-oriented innovation policy for transformative innovation in Japan:historical development and lessons from the case of automated driving 197Kazuhito Oyamada and Tateo Arimoto10 The spatial and scalar implications of missions: challenges andopportunities for policy 218Elvira Uyarra, Iris Wanzenböck and Kieron Flanagan11 Transformative innovation policy in the making: how directionality hasemerged for mobility as a service in Finland 237Paula Kivimaa and Jonas Torrens12 The transformative potential of Horizon Europe RI Partnerships in theareas of climate, energy, and mobility 258Katharina Berger, Christoph Brodnik and Michael DingesPART III EMPIRICAL COMPARISON OF DIFFERENT TYPES OFTRANSFORMATIONAL AREAS13 Achilles’ heels of acceleration? Assessing critical capacity fortransformative policy mixes 283Karoline S. Rogge and Qi Song14 Transformative missions in healthcare: the case of preventive healthcare inthe Netherlands 302Wouter Boon15 Governance arrangements for the implementation of transformativeinnovation policy: insights from a comparative case study 318Matthijs Janssen, Iris Wanzenböck, Lea Fünfschilling and Dimitrios PontikakisPART IV IMPLEMENTING TRANSFORMATIVE MISSION-ORIENTED STIPOLICY16 Programming missions: steering a mission-oriented research programmethrough the production and use of strategic intelligence 348Douglas K. R. Robinson, Mireille Matt and Renée van Dis17 The governance of transformative mission-oriented STI policies 368Jakob Edler and Matthias Weber

‘The rich set of experimental cases presented in this volume provides a strong foundation for learning across the different dimensions and phases of mission-oriented STI policy, including governance and capacity building. [...] It offers an indispensable resource for scholars and policymakers dedicated to guiding long-term, sustainable societal change, providing a clear and optimistic path forward for the future of innovation policy.’

Edited by Jakob Edler, Managing Director, Fraunhofer Institute for Systems and Innovation Research ISI, Germany and Professor of Innovation Policy and Strategy, University of Manchester, UK, Mireille Matt, Senior Research Scientist, French National Institute for Research on Agriculture, Food and Environment (INRAE), France, Wolfgang Polt, Formerly Director of POLICIES, Joanneum Research, Austria and Matthias Weber, Head, Center for Innovation Systems and Policy, AIT (Austrian Institute of Technology), Austria and Professor of Innovation Policy, Université Gustave Eiffel, France

• ContentsIntroduction: the motivation for this volume and an overview of its contributions 1Jakob Edler, Mireille Matt, Wolfgang Polt and Matthias WeberPART I TRANSFORMATIVE MISSION-ORIENTED STI POLICY: THEORYAND CONCEPT1 Transformative mission-oriented STI policy: theoretical and conceptualrationales, intervention logics and challenges of an emerging type of STIpolicies 16Jakob Edler, Mireille Matt, Wolfgang Polt and Matthias Weber2 From formulation to implementation: conceptualizing mission-orientedpolicies as multi-stage translation processes 36Florian Wittmann, Miriam Hufnagl, Florian Roth, Merve Yorulmaz,Ralf Lindner and Stephanie Daimer3 Missions as a boundary object in umbrella frameworks: the case of theDutch mission-oriented top sector and innovation policy 53Matthijs Janssen, Joeri Wesseling, Jonas Torrens, Matthias Weber andCaetano C. R. PennaPART II TRANSFORMATIVE MISSION-ORIENTED STI POLICIES INDIFFERENT POLITICAL SYSTEMS AND ON DIFFERENT LEVELS4 Mission-oriented innovation policies in Europe: from the normative to theepistemic turn? 78Rainer Kattel and Mariana Mazzucato5 The formative evaluation of open-ended transformative missions: theVinnova experience in the food system 97Caetano C. R. Penna, Johan Schot, Diana Velasco and Jordi Molas-Gallart6 Challenges and opportunities of mission-oriented innovation policies forrealising transformative agendas: general principles and application to thecase of the fight against climate change 118Philippe Larrue7 Transformative missions as part of sustainability research programmes:experiences from the German FONA framework programme 144Rainer Walz, Susanne Bührer and Sarah Seus8 Conversion of the green mission for transformation-oriented industrialinnovation: green growth and 2050 carbon neutrality in South Korea 171Soohong Eum9 Mission-oriented innovation policy for transformative innovation in Japan:historical development and lessons from the case of automated driving 197Kazuhito Oyamada and Tateo Arimoto10 The spatial and scalar implications of missions: challenges andopportunities for policy 218Elvira Uyarra, Iris Wanzenböck and Kieron Flanagan11 Transformative innovation policy in the making: how directionality hasemerged for mobility as a service in Finland 237Paula Kivimaa and Jonas Torrens12 The transformative potential of Horizon Europe RI Partnerships in theareas of climate, energy, and mobility 258Katharina Berger, Christoph Brodnik and Michael DingesPART III EMPIRICAL COMPARISON OF DIFFERENT TYPES OFTRANSFORMATIONAL AREAS13 Achilles’ heels of acceleration? Assessing critical capacity fortransformative policy mixes 283Karoline S. Rogge and Qi Song14 Transformative missions in healthcare: the case of preventive healthcare inthe Netherlands 302Wouter Boon15 Governance arrangements for the implementation of transformativeinnovation policy: insights from a comparative case study 318Matthijs Janssen, Iris Wanzenböck, Lea Fünfschilling and Dimitrios PontikakisPART IV IMPLEMENTING TRANSFORMATIVE MISSION-ORIENTED STIPOLICY16 Programming missions: steering a mission-oriented research programmethrough the production and use of strategic intelligence 348Douglas K. R. Robinson, Mireille Matt and Renée van Dis17 The governance of transformative mission-oriented STI policies 368Jakob Edler and Matthias Weber

‘The rich set of experimental cases presented in this volume provides a strong foundation for learning across the different dimensions and phases of mission-oriented STI policy, including governance and capacity building. [...] It offers an indispensable resource for scholars and policymakers dedicated to guiding long-term, sustainable societal change, providing a clear and optimistic path forward for the future of innovation policy.’

Edited by Jakob Edler, Managing Director, Fraunhofer Institute for Systems and Innovation Research ISI, Germany and Professor of Innovation Policy and Strategy, University of Manchester, UK, Mireille Matt, Senior Research Scientist, French National Institute for Research on Agriculture, Food and Environment (INRAE), France, Wolfgang Polt, Formerly Director of POLICIES, Joanneum Research, Austria and Matthias Weber, Head, Center for Innovation Systems and Policy, AIT (Austrian Institute of Technology), Austria and Professor of Innovation Policy, Université Gustave Eiffel, France

• ContentsIntroduction: the motivation for this volume and an overview of its contributions 1Jakob Edler, Mireille Matt, Wolfgang Polt and Matthias WeberPART I TRANSFORMATIVE MISSION-ORIENTED STI POLICY: THEORYAND CONCEPT1 Transformative mission-oriented STI policy: theoretical and conceptualrationales, intervention logics and challenges of an emerging type of STIpolicies 16Jakob Edler, Mireille Matt, Wolfgang Polt and Matthias Weber2 From formulation to implementation: conceptualizing mission-orientedpolicies as multi-stage translation processes 36Florian Wittmann, Miriam Hufnagl, Florian Roth, Merve Yorulmaz,Ralf Lindner and Stephanie Daimer3 Missions as a boundary object in umbrella frameworks: the case of theDutch mission-oriented top sector and innovation policy 53Matthijs Janssen, Joeri Wesseling, Jonas Torrens, Matthias Weber andCaetano C. R. PennaPART II TRANSFORMATIVE MISSION-ORIENTED STI POLICIES INDIFFERENT POLITICAL SYSTEMS AND ON DIFFERENT LEVELS4 Mission-oriented innovation policies in Europe: from the normative to theepistemic turn? 78Rainer Kattel and Mariana Mazzucato5 The formative evaluation of open-ended transformative missions: theVinnova experience in the food system 97Caetano C. R. Penna, Johan Schot, Diana Velasco and Jordi Molas-Gallart6 Challenges and opportunities of mission-oriented innovation policies forrealising transformative agendas: general principles and application to thecase of the fight against climate change 118Philippe Larrue7 Transformative missions as part of sustainability research programmes:experiences from the German FONA framework programme 144Rainer Walz, Susanne Bührer and Sarah Seus8 Conversion of the green mission for transformation-oriented industrialinnovation: green growth and 2050 carbon neutrality in South Korea 171Soohong Eum9 Mission-oriented innovation policy for transformative innovation in Japan:historical development and lessons from the case of automated driving 197Kazuhito Oyamada and Tateo Arimoto10 The spatial and scalar implications of missions: challenges andopportunities for policy 218Elvira Uyarra, Iris Wanzenböck and Kieron Flanagan11 Transformative innovation policy in the making: how directionality hasemerged for mobility as a service in Finland 237Paula Kivimaa and Jonas Torrens12 The transformative potential of Horizon Europe RI Partnerships in theareas of climate, energy, and mobility 258Katharina Berger, Christoph Brodnik and Michael DingesPART III EMPIRICAL COMPARISON OF DIFFERENT TYPES OFTRANSFORMATIONAL AREAS13 Achilles’ heels of acceleration? Assessing critical capacity fortransformative policy mixes 283Karoline S. Rogge and Qi Song14 Transformative missions in healthcare: the case of preventive healthcare inthe Netherlands 302Wouter Boon15 Governance arrangements for the implementation of transformativeinnovation policy: insights from a comparative case study 318Matthijs Janssen, Iris Wanzenböck, Lea Fünfschilling and Dimitrios PontikakisPART IV IMPLEMENTING TRANSFORMATIVE MISSION-ORIENTED STIPOLICY16 Programming missions: steering a mission-oriented research programmethrough the production and use of strategic intelligence 348Douglas K. R. Robinson, Mireille Matt and Renée van Dis17 The governance of transformative mission-oriented STI policies 368Jakob Edler and Matthias Weber

‘The rich set of experimental cases presented in this volume provides a strong foundation for learning across the different dimensions and phases of mission-oriented STI policy, including governance and capacity building. [...] It offers an indispensable resource for scholars and policymakers dedicated to guiding long-term, sustainable societal change, providing a clear and optimistic path forward for the future of innovation policy.’